TRDN-AS1

Summary

TRDN-AS1 (TRDN antisense RNA 1, HGNC:40592) is a long non-coding RNA gene on chromosome 6q22.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40592
Approved symbol	TRDN-AS1
Name	TRDN antisense RNA 1
Location	6q22.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	HRAT13
Ensembl gene	ENSG00000235535
Ensembl biotype	lncRNA
Entrez	101927990
RNAcentral	URS000075B0AE — lncRNA, 2409 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000418467, ENST00000427828, ENST00000434768, ENST00000587049, ENST00000587106, ENST00000589182, ENST00000610906, ENST00000615864, ENST00000618357, ENST00000619147, ENST00000625262, ENST00000625415, ENST00000628939, ENST00000629087, ENST00000655724, ENST00000656482, ENST00000668867, ENST00000669371, ENST00000670687, ENST00000686678, ENST00000761437, ENST00000761438, ENST00000761439, ENST00000761440, ENST00000761441, ENST00000761442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418467 — 3 exons

Exon	Start	End
ENSE00001597482	123468800	123468930
ENSE00002841423	123469637	123471759
ENSE00004115690	123439530	123439777

Expression profiles

Bgee: expression breadth ubiquitous, 137 present calls, max score 98.03.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6550 / max 263.5540, expressed in 21 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
69576	0.2057	13
69578	0.1970	12
69577	0.1423	11
69579	0.0704	9
69575	0.0168	7
69581	0.0089	5
69580	0.0079	4
204187	0.0060	5

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
apex of heart	UBERON:0002098	98.03	gold quality
heart left ventricle	UBERON:0002084	96.93	gold quality
cardiac ventricle	UBERON:0002082	96.44	gold quality
colonic epithelium	UBERON:0000397	91.83	gold quality
heart	UBERON:0000948	89.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.37	gold quality
right atrium auricular region	UBERON:0006631	86.02	gold quality
cardiac atrium	UBERON:0002081	85.06	gold quality
heart right ventricle	UBERON:0002080	84.21	gold quality
bone marrow cell	CL:0002092	82.89	gold quality
ganglionic eminence	UBERON:0004023	82.62	gold quality
myocardium	UBERON:0002349	81.99	gold quality
hindlimb stylopod muscle	UBERON:0004252	79.32	gold quality
cortical plate	UBERON:0005343	77.36	gold quality
adrenal tissue	UBERON:0018303	77.31	gold quality
sural nerve	UBERON:0015488	75.27	gold quality
ventricular zone	UBERON:0003053	74.86	gold quality
tonsil	UBERON:0002372	71.55	gold quality
uterine cervix	UBERON:0000002	69.65	gold quality
gall bladder	UBERON:0002110	68.49	gold quality
muscle of leg	UBERON:0001383	64.91	gold quality
gastrocnemius	UBERON:0001388	64.57	gold quality
adenohypophysis	UBERON:0002196	62.54	gold quality
prefrontal cortex	UBERON:0000451	60.75	gold quality
muscle layer of sigmoid colon	UBERON:0035805	58.87	gold quality
pituitary gland	UBERON:0000007	58.65	gold quality
monocyte	CL:0000576	58.09	gold quality
urinary bladder	UBERON:0001255	55.94	gold quality
skeletal muscle tissue	UBERON:0001134	54.97	gold quality
bone marrow	UBERON:0002371	54.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.