TRG-CCC3-1

Summary

TRG-CCC3-1 (tRNA-Gly (anticodon CCC) 3-1, HGNC:34841) is a gene on chromosome 17p11.2.

At a glance

• Clinical variants (ClinVar): 2 total — 2 pathogenic

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:34841
Approved symbol	TRG-CCC3-1
Name	tRNA-Gly (anticodon CCC) 3-1
Location	17p11.2
Locus type	RNA, transfer
Status	Approved
Aliases	tRNA-Gly-CCC-3-1
Entrez	100189277
RNAcentral	URS0000684E4B — tRNA, 71 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

2 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	2
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (2)

Variant ID	HGVS	Classification
150379	GRCh38/hg38 17p11.2(chr17:16989087-20370816)x1	Pathogenic
155110	GRCh38/hg38 17p12-11.2(chr17:15883037-20658018)x1	Pathogenic

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.