TRIDDENT

Summary

TRIDDENT (TRIM28 interacting DNA damage repair enhancing non-coding transcript, HGNC:54406) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54406
Approved symbol	TRIDDENT
Name	TRIM28 interacting DNA damage repair enhancing non-coding transcript
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-462G12.2, TRIDENT
Ensembl gene	ENSG00000262185
Ensembl biotype	lncRNA
Entrez	102724927
RNAcentral	URS000022F0D9 — lncRNA, 1394 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000571302, ENST00000576810, ENST00000649221, ENST00000657721

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000571302 — 3 exons

Exon	Start	End
ENSE00002664480	3943260	3943375
ENSE00002665558	3946153	3946305
ENSE00002674653	3930806	3931721

Expression profiles

Bgee: expression breadth ubiquitous, 164 present calls, max score 81.47.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4360 / max 27.5033, expressed in 246 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
156051	0.1700	104
156050	0.1505	69
156052	0.1155	49

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
descending thoracic aorta	UBERON:0002345	81.47	gold quality
thoracic aorta	UBERON:0001515	81.11	gold quality
ascending aorta	UBERON:0001496	81.05	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.35	gold quality
endothelial cell	CL:0000115	77.67	silver quality
aorta	UBERON:0000947	76.73	gold quality
stromal cell of endometrium	CL:0002255	74.55	gold quality
buccal mucosa cell	CL:0002336	74.36	gold quality
right coronary artery	UBERON:0001625	73.95	gold quality
tibial artery	UBERON:0007610	73.59	gold quality
popliteal artery	UBERON:0002250	73.58	gold quality
left coronary artery	UBERON:0001626	71.23	gold quality
left lobe of thyroid gland	UBERON:0001120	70.46	gold quality
coronary artery	UBERON:0001621	69.77	gold quality
thyroid gland	UBERON:0002046	69.76	gold quality
right lobe of thyroid gland	UBERON:0001119	69.62	gold quality
sural nerve	UBERON:0015488	68.85	silver quality
tibial nerve	UBERON:0001323	67.09	gold quality
bone marrow cell	CL:0002092	66.57	silver quality
right lung	UBERON:0002167	66.18	gold quality
upper lobe of left lung	UBERON:0008952	66.15	gold quality
upper lobe of lung	UBERON:0008948	65.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.34	gold quality
right atrium auricular region	UBERON:0006631	64.79	gold quality
cortical plate	UBERON:0005343	64.69	gold quality
right adrenal gland cortex	UBERON:0035827	64.28	gold quality
cardiac atrium	UBERON:0002081	64.16	gold quality
colonic epithelium	UBERON:0000397	63.98	silver quality
right adrenal gland	UBERON:0001233	63.79	gold quality
apex of heart	UBERON:0002098	63.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.