TROAP-AS1

Summary

TROAP-AS1 (TROAP and PRPH antisense RNA 1, HGNC:55453) is a long non-coding RNA gene on chromosome 12q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55453
Approved symbol	TROAP-AS1
Name	TROAP and PRPH antisense RNA 1
Location	12q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258334
Ensembl biotype	lncRNA
Entrez	101927267
RNAcentral	URS000057AC12 — lncRNA, 4166 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000553259, ENST00000797029, ENST00000797030, ENST00000797031, ENST00000797032, ENST00000797033

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553259 — 8 exons

Exon	Start	End
ENSE00002168097	49295260	49296584
ENSE00002350385	49303100	49303230
ENSE00002385054	49324147	49324339
ENSE00002387082	49296716	49297706
ENSE00002390120	49324492	49324576
ENSE00002399627	49294448	49294535
ENSE00002407669	49292631	49293896
ENSE00002418667	49303806	49303892

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 77.68.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	77.68	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.01	gold quality
fallopian tube	UBERON:0003889	57.77	gold quality
prefrontal cortex	UBERON:0000451	51.93	silver quality
right frontal lobe	UBERON:0002810	51.23	gold quality
blood	UBERON:0000178	51.00	gold quality
cerebral cortex	UBERON:0000956	49.68	gold quality
pancreas	UBERON:0001264	48.33	gold quality
islet of Langerhans	UBERON:0000006	48.20	gold quality
adrenal gland	UBERON:0002369	47.63	gold quality
right lung	UBERON:0002167	47.58	gold quality
endometrium	UBERON:0001295	47.37	silver quality
duodenum	UBERON:0002114	47.26	silver quality
caudate nucleus	UBERON:0001873	47.19	gold quality
left uterine tube	UBERON:0001303	47.17	gold quality
smooth muscle tissue	UBERON:0001135	46.96	gold quality
Ammon’s horn	UBERON:0001954	46.94	gold quality
cerebellum	UBERON:0002037	46.90	gold quality
lung	UBERON:0002048	46.89	gold quality
left adrenal gland	UBERON:0001234	46.86	gold quality
cerebellar cortex	UBERON:0002129	46.63	gold quality
cerebellar hemisphere	UBERON:0002245	46.59	gold quality
left adrenal gland cortex	UBERON:0035825	46.50	gold quality
body of uterus	UBERON:0009853	46.01	gold quality
right adrenal gland	UBERON:0001233	45.76	gold quality
upper lobe of left lung	UBERON:0008952	45.60	gold quality
nucleus accumbens	UBERON:0001882	45.39	gold quality
left coronary artery	UBERON:0001626	45.23	gold quality
endocervix	UBERON:0000458	44.76	gold quality
lymph node	UBERON:0000029	44.36	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.54

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.