TSHR-AS1

Summary

TSHR-AS1 (TSHR antisense RNA 1, HGNC:58172) is a long non-coding RNA gene on chromosome 14q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58172
Approved symbol	TSHR-AS1
Name	TSHR antisense RNA 1
Location	14q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000284959
Ensembl biotype	lncRNA
Entrez	101928462
RNAcentral	URS0000D622CE — lncRNA, 5577 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000646052, ENST00000646928, ENST00000652775, ENST00000654681, ENST00000663571, ENST00000701732, ENST00000788233, ENST00000788234, ENST00000788235, ENST00000788236, ENST00000788237, ENST00000788238, ENST00000788239, ENST00000788240, ENST00000788241, ENST00000788242, ENST00000788243, ENST00000788244, ENST00000788245, ENST00000788246, ENST00000788247, ENST00000788248, ENST00000788249, ENST00000788250

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000646052 — 8 exons

Exon	Start	End
ENSE00002481931	81165193	81165381
ENSE00003814645	81094215	81094324
ENSE00003814735	81099399	81099526
ENSE00003818123	81053683	81053816
ENSE00003819267	81012099	81014404
ENSE00003819446	81093582	81093737
ENSE00003821237	81087467	81087652
ENSE00003877821	81170109	81170429

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 83.16.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.16	gold quality
right lobe of thyroid gland	UBERON:0001119	80.61	gold quality
thyroid gland	UBERON:0002046	79.92	gold quality
left lobe of thyroid gland	UBERON:0001120	79.66	gold quality
right lobe of liver	UBERON:0001114	78.92	gold quality
liver	UBERON:0002107	77.73	gold quality
colonic epithelium	UBERON:0000397	76.54	gold quality
bone marrow cell	CL:0002092	74.71	gold quality
monocyte	CL:0000576	74.03	gold quality
leukocyte	CL:0000738	72.90	gold quality
tonsil	UBERON:0002372	68.75	gold quality
skeletal muscle tissue	UBERON:0001134	68.73	gold quality
bone marrow	UBERON:0002371	68.20	gold quality
right adrenal gland cortex	UBERON:0035827	66.87	gold quality
muscle tissue	UBERON:0002385	66.83	gold quality
ventricular zone	UBERON:0003053	66.44	gold quality
ganglionic eminence	UBERON:0004023	66.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.10	silver quality
right adrenal gland	UBERON:0001233	65.86	gold quality
corpus callosum	UBERON:0002336	65.19	gold quality
left adrenal gland	UBERON:0001234	64.66	gold quality
left adrenal gland cortex	UBERON:0035825	64.40	gold quality
adrenal gland	UBERON:0002369	64.01	gold quality
superior frontal gyrus	UBERON:0002661	63.63	gold quality
left uterine tube	UBERON:0001303	63.46	gold quality
pituitary gland	UBERON:0000007	63.07	gold quality
endometrium	UBERON:0001295	62.84	gold quality
myometrium	UBERON:0001296	61.88	gold quality
nucleus accumbens	UBERON:0001882	61.62	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	61.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.