TSPAN5-DT

Summary

TSPAN5-DT (TSPAN5 divergent transcript, HGNC:55389) is a long non-coding RNA gene on chromosome 4q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55389
Approved symbol	TSPAN5-DT
Name	TSPAN5 divergent transcript
Location	4q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260641
Ensembl biotype	lncRNA
Entrez	105377342
RNAcentral	URS0000BC4506 — lncRNA, 1812 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000569927, ENST00000802021, ENST00000802022, ENST00000802023, ENST00000802024, ENST00000802025, ENST00000802026, ENST00000802027, ENST00000802028, ENST00000802029, ENST00000802030, ENST00000802031, ENST00000802032, ENST00000802033, ENST00000802034

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000569927 — 1 exons

Exon	Start	End
ENSE00004191863	98658879	98664550

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 73.74.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4395 / max 57.1844, expressed in 147 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
48981	0.3586	118
48982	0.0808	24

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar cortex	UBERON:0002129	73.74	gold quality
cerebellar hemisphere	UBERON:0002245	73.74	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.69	gold quality
cerebellum	UBERON:0002037	73.60	gold quality
cerebellar vermis	UBERON:0004720	72.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	70.94	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
thymus	UBERON:0002370	69.08	silver quality
ventricular zone	UBERON:0003053	68.06	gold quality
ganglionic eminence	UBERON:0004023	67.15	gold quality
prefrontal cortex	UBERON:0000451	66.43	gold quality
superior frontal gyrus	UBERON:0002661	65.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.02	gold quality
frontal cortex	UBERON:0001870	64.94	gold quality
spinal cord	UBERON:0002240	64.38	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	64.36	gold quality
cerebral cortex	UBERON:0000956	62.99	gold quality
cortical plate	UBERON:0005343	62.87	gold quality
right frontal lobe	UBERON:0002810	62.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.60	gold quality
primary visual cortex	UBERON:0002436	61.97	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.96	gold quality
substantia nigra	UBERON:0002038	61.92	gold quality
stromal cell of endometrium	CL:0002255	61.81	gold quality
Ammon’s horn	UBERON:0001954	61.69	gold quality
brain	UBERON:0000955	61.38	gold quality
anterior cingulate cortex	UBERON:0009835	60.54	gold quality
skeletal muscle tissue	UBERON:0001134	60.13	silver quality
bone marrow	UBERON:0002371	59.18	gold quality
corpus callosum	UBERON:0002336	59.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.