TTBK2-AS1

Summary

TTBK2-AS1 (TTBK2 antisense RNA 1, HGNC:55598) is a long non-coding RNA gene on chromosome 15q15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55598
Approved symbol	TTBK2-AS1
Name	TTBK2 antisense RNA 1
Location	15q15.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246283
Ensembl biotype	lncRNA
Entrez	121676926
RNAcentral	URS00026A1E2E — lncRNA, 1430 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000500850, ENST00000567456, ENST00000804552, ENST00000804553, ENST00000804554, ENST00000804555

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500850 — 2 exons

Exon	Start	End
ENSE00001988432	42740748	42741563
ENSE00002588053	42742002	42743202

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 93.29.

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	93.29	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.01	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.57	gold quality
tendon of biceps brachii	UBERON:0008188	83.41	gold quality
sural nerve	UBERON:0015488	81.78	gold quality
colonic epithelium	UBERON:0000397	81.57	gold quality
cortical plate	UBERON:0005343	79.61	gold quality
medial globus pallidus	UBERON:0002477	78.75	gold quality
tendon	UBERON:0000043	76.86	gold quality
ventricular zone	UBERON:0003053	76.69	gold quality
ganglionic eminence	UBERON:0004023	75.83	gold quality
stromal cell of endometrium	CL:0002255	72.45	gold quality
bone marrow cell	CL:0002092	72.24	silver quality
left testis	UBERON:0004533	72.10	gold quality
right testis	UBERON:0004534	71.89	gold quality
testis	UBERON:0000473	71.51	gold quality
globus pallidus	UBERON:0001875	70.77	gold quality
oviduct epithelium	UBERON:0004804	70.65	gold quality
prefrontal cortex	UBERON:0000451	70.49	gold quality
leukocyte	CL:0000738	67.36	gold quality
monocyte	CL:0000576	67.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.90	gold quality
right coronary artery	UBERON:0001625	65.28	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.22	gold quality
tibial artery	UBERON:0007610	65.09	gold quality
popliteal artery	UBERON:0002250	65.08	gold quality
sperm	CL:0000019	63.46	silver quality
frontal cortex	UBERON:0001870	63.27	gold quality
neocortex	UBERON:0001950	62.97	gold quality
cerebellar cortex	UBERON:0002129	62.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.