TTC12-DT

Summary

TTC12-DT (TTC12 divergent transcript, HGNC:55508) is a long non-coding RNA gene on chromosome 11q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55508
Approved symbol	TTC12-DT
Name	TTC12 divergent transcript
Location	11q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255129
Ensembl biotype	lncRNA
Entrez	124902814
RNAcentral	URS00026A2615 — lncRNA, 736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000526487, ENST00000529416, ENST00000533504

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000526487 — 4 exons

Exon	Start	End
ENSE00002144702	113278250	113278743
ENSE00002165917	113279490	113279649
ENSE00002196642	113280491	113280632
ENSE00002201787	113314330	113314482

Expression profiles

Bgee: expression breadth ubiquitous, 182 present calls, max score 89.63.

Top tissues by expression

256 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	89.63	gold quality
medial globus pallidus	UBERON:0002477	85.44	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.34	gold quality
middle temporal gyrus	UBERON:0002771	80.34	gold quality
Brodmann (1909) area 46	UBERON:0006483	80.31	gold quality
globus pallidus	UBERON:0001875	80.16	gold quality
buccal mucosa cell	CL:0002336	79.43	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.34	gold quality
ventricular zone	UBERON:0003053	78.07	gold quality
ganglionic eminence	UBERON:0004023	77.77	gold quality
prefrontal cortex	UBERON:0000451	75.95	gold quality
primary visual cortex	UBERON:0002436	75.66	gold quality
caudate nucleus	UBERON:0001873	75.54	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	75.51	gold quality
pons	UBERON:0000988	75.16	gold quality
neocortex	UBERON:0001950	75.09	gold quality
nucleus accumbens	UBERON:0001882	74.95	gold quality
putamen	UBERON:0001874	74.93	gold quality
anterior cingulate cortex	UBERON:0009835	74.89	gold quality
frontal cortex	UBERON:0001870	74.67	gold quality
right frontal lobe	UBERON:0002810	74.63	gold quality
paraflocculus	UBERON:0005351	74.45	gold quality
cerebral cortex	UBERON:0000956	74.39	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.11	gold quality
forebrain	UBERON:0001890	73.44	gold quality
entorhinal cortex	UBERON:0002728	73.44	gold quality
Brodmann (1909) area 23	UBERON:0013554	73.35	gold quality
middle frontal gyrus	UBERON:0002702	73.15	gold quality
brain	UBERON:0000955	73.09	gold quality
central nervous system	UBERON:0001017	72.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.