TTC3-AS1

Summary

TTC3-AS1 (TTC3 antisense RNA 1, HGNC:40595) is a long non-coding RNA gene on chromosome 21q22.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40595
Approved symbol	TTC3-AS1
Name	TTC3 antisense RNA 1
Location	21q22.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228677
Ensembl biotype	lncRNA
Entrez	100874006
RNAcentral	URS00008BAEC8 — lncRNA, 1151 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424733

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424733 — 2 exons

Exon	Start	End
ENSE00001619558	37193808	37193926
ENSE00001652211	37187666	37188643

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 75.79.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.79	gold quality
sural nerve	UBERON:0015488	71.69	gold quality
adrenal tissue	UBERON:0018303	67.86	gold quality
colonic epithelium	UBERON:0000397	66.00	silver quality
bone marrow cell	CL:0002092	65.51	silver quality
ventricular zone	UBERON:0003053	63.52	gold quality
bone marrow	UBERON:0002371	63.11	silver quality
skeletal muscle tissue	UBERON:0001134	61.95	gold quality
ganglionic eminence	UBERON:0004023	60.83	gold quality
corpus callosum	UBERON:0002336	56.73	gold quality
tonsil	UBERON:0002372	56.69	silver quality
liver	UBERON:0002107	55.12	gold quality
left ovary	UBERON:0002119	55.02	gold quality
calcaneal tendon	UBERON:0003701	54.98	gold quality
ovary	UBERON:0000992	54.86	gold quality
leukocyte	CL:0000738	54.75	silver quality
lower esophagus mucosa	UBERON:0035834	54.64	gold quality
stromal cell of endometrium	CL:0002255	54.18	silver quality
monocyte	CL:0000576	53.92	silver quality
right ovary	UBERON:0002118	53.76	gold quality
pituitary gland	UBERON:0000007	53.52	gold quality
adenohypophysis	UBERON:0002196	53.45	gold quality
right lobe of liver	UBERON:0001114	52.97	gold quality
minor salivary gland	UBERON:0001830	52.56	gold quality
prostate gland	UBERON:0002367	52.55	gold quality
saliva-secreting gland	UBERON:0001044	52.46	gold quality
endometrium	UBERON:0001295	52.42	gold quality
islet of Langerhans	UBERON:0000006	52.27	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	51.89	silver quality
primary visual cortex	UBERON:0002436	51.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.