TTLL1-AS1

Summary

TTLL1-AS1 (TTLL1 antisense RNA 1, HGNC:40111) is a long non-coding RNA gene on chromosome 22q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40111
Approved symbol	TTLL1-AS1
Name	TTLL1 antisense RNA 1
Location	22q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230319
Ensembl biotype	lncRNA
Entrez	100506679
RNAcentral	URS000075B135 — lncRNA, 2096 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000443063, ENST00000733776, ENST00000733777, ENST00000733778, ENST00000733779, ENST00000733780, ENST00000733781, ENST00000733782, ENST00000733783, ENST00000733784, ENST00000733785

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443063 — 3 exons

Exon	Start	End
ENSE00001629929	43038585	43040264
ENSE00001634800	43041211	43041301
ENSE00001782170	43052055	43052366

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 78.02.

Top tissues by expression

222 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.02	gold quality
buccal mucosa cell	CL:0002336	72.56	silver quality
cortical plate	UBERON:0005343	70.46	gold quality
ganglionic eminence	UBERON:0004023	63.39	gold quality
ventricular zone	UBERON:0003053	60.32	gold quality
cerebellar hemisphere	UBERON:0002245	60.27	gold quality
cerebellar cortex	UBERON:0002129	60.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.27	gold quality
prefrontal cortex	UBERON:0000451	59.01	gold quality
cerebellum	UBERON:0002037	58.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.70	gold quality
stromal cell of endometrium	CL:0002255	58.37	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.17	silver quality
right frontal lobe	UBERON:0002810	57.09	gold quality
anterior cingulate cortex	UBERON:0009835	56.96	gold quality
calcaneal tendon	UBERON:0003701	56.77	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	55.83	gold quality
neocortex	UBERON:0001950	55.23	gold quality
frontal cortex	UBERON:0001870	54.89	gold quality
skin of hip	UBERON:0001554	53.81	silver quality
cerebral cortex	UBERON:0000956	52.98	gold quality
hypothalamus	UBERON:0001898	52.98	gold quality
tendon of biceps brachii	UBERON:0008188	52.90	gold quality
amygdala	UBERON:0001876	52.84	gold quality
leukocyte	CL:0000738	52.41	silver quality
apex of heart	UBERON:0002098	52.27	gold quality
monocyte	CL:0000576	52.22	silver quality
brain	UBERON:0000955	51.62	gold quality
nucleus accumbens	UBERON:0001882	51.58	gold quality
parotid gland	UBERON:0001831	51.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.