TTLL7-IT1

Summary

TTLL7-IT1 (TTLL7 intronic transcript 1, HGNC:41486) is a long non-coding RNA gene on chromosome 1p31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41486
Approved symbol	TTLL7-IT1
Name	TTLL7 intronic transcript 1
Location	1p31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233061
Ensembl biotype	lncRNA
Entrez	100874314
RNAcentral	URS00004A36D3 — lncRNA, 2921 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000455929

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455929 — 2 exons

Exon	Start	End
ENSE00001623203	83979118	83981569
ENSE00001725209	83983832	83984300

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 75.38.

Top tissues by expression

184 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.38	gold quality
bone marrow cell	CL:0002092	71.61	gold quality
colonic epithelium	UBERON:0000397	65.39	silver quality
buccal mucosa cell	CL:0002336	63.58	gold quality
corpus callosum	UBERON:0002336	63.23	gold quality
lower lobe of lung	UBERON:0008949	61.90	silver quality
sural nerve	UBERON:0015488	61.21	gold quality
cortical plate	UBERON:0005343	59.46	gold quality
sperm	CL:0000019	59.37	silver quality
monocyte	CL:0000576	52.79	silver quality
hindlimb stylopod muscle	UBERON:0004252	51.28	silver quality
adrenal tissue	UBERON:0018303	51.02	silver quality
calcaneal tendon	UBERON:0003701	50.28	silver quality
tonsil	UBERON:0002372	50.13	silver quality
medial globus pallidus	UBERON:0002477	49.11	silver quality
uterine cervix	UBERON:0000002	49.05	silver quality
prefrontal cortex	UBERON:0000451	48.89	gold quality
muscle of leg	UBERON:0001383	47.99	silver quality
islet of Langerhans	UBERON:0000006	47.41	gold quality
ascending aorta	UBERON:0001496	47.13	gold quality
globus pallidus	UBERON:0001875	47.09	silver quality
descending thoracic aorta	UBERON:0002345	46.93	gold quality
thoracic aorta	UBERON:0001515	46.92	gold quality
upper lobe of lung	UBERON:0008948	46.80	silver quality
tendon	UBERON:0000043	46.61	silver quality
aorta	UBERON:0000947	46.54	gold quality
popliteal artery	UBERON:0002250	46.32	gold quality
tibial artery	UBERON:0007610	46.25	gold quality
pancreas	UBERON:0001264	45.96	silver quality
stomach	UBERON:0000945	45.68	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.