TTTY1

Summary

TTTY1 (testis expressed transcript, Y-linked 1, HGNC:14022) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14022
Approved symbol	TTTY1
Name	testis expressed transcript, Y-linked 1
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	TTY1, NCRNA00033, LINC00033
Ensembl gene	ENSG00000129845
Ensembl biotype	lncRNA
Entrez	50858
RNAcentral	URS00008121DB — lncRNA, 950 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000250805, ENST00000805314

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000250805 — 5 exons

Exon	Start	End
ENSE00001609985	9753156	9753413
ENSE00001664883	9770461	9770620
ENSE00001771159	9760995	9761132
ENSE00001782128	9774045	9774289
ENSE00001800396	9763489	9763597

Expression profiles

Bgee: expression breadth broad, 22 present calls, max score 80.15.

Top tissues by expression

22 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.15	gold quality
gall bladder	UBERON:0002110	52.14	gold quality
Ammon’s horn	UBERON:0001954	47.02	gold quality
right testis	UBERON:0004534	46.12	gold quality
body of pancreas	UBERON:0001150	45.21	silver quality
prostate gland	UBERON:0002367	45.21	silver quality
testis	UBERON:0000473	44.66	gold quality
muscle layer of sigmoid colon	UBERON:0035805	44.53	gold quality
stomach	UBERON:0000945	44.08	gold quality
left testis	UBERON:0004533	44.01	gold quality
saliva-secreting gland	UBERON:0001044	43.71	gold quality
right lobe of liver	UBERON:0001114	43.46	silver quality
minor salivary gland	UBERON:0001830	42.84	gold quality
small intestine	UBERON:0002108	42.63	silver quality
transverse colon	UBERON:0001157	40.56	silver quality
small intestine Peyer’s patch	UBERON:0003454	40.24	silver quality
skin of leg	UBERON:0001511	40.14	silver quality
skin of abdomen	UBERON:0001416	39.29	silver quality
nucleus accumbens	UBERON:0001882	39.05	silver quality
hypothalamus	UBERON:0001898	37.79	silver quality
esophagus mucosa	UBERON:0002469	36.78	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	34.91	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.