TTTY10

Summary

TTTY10 (testis expressed transcript, Y-linked 10, HGNC:18491) is a long non-coding RNA gene on chromosome Yq11.223.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18491
Approved symbol	TTTY10
Name	testis expressed transcript, Y-linked 10
Location	Yq11.223
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00133, lnc-KDM5D-4
Ensembl gene	ENSG00000229236
Ensembl biotype	lncRNA
Entrez	246119
RNAcentral	URS000007C6F9 — lncRNA, 1628 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000455084, ENST00000651837, ENST00000654569, ENST00000657696, ENST00000658891, ENST00000659275, ENST00000660111, ENST00000661812, ENST00000662223, ENST00000666666, ENST00000666990, ENST00000667496, ENST00000670518, ENST00000755216, ENST00000755217, ENST00000755218, ENST00000755219, ENST00000755220

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455084 — 6 exons

Exon	Start	End
ENSE00001646929	20466428	20466667
ENSE00001669312	20468189	20468248
ENSE00001688639	20507352	20507456
ENSE00001717483	20465668	20465822
ENSE00001719273	20469872	20469981
ENSE00001757026	20518271	20519228

Expression profiles

Bgee: expression breadth ubiquitous, 144 present calls, max score 87.55.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7008 / max 26.0996, expressed in 303 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201282	0.3050	140
201283	0.2339	138
201281	0.1619	88

Top tissues by expression

233 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.55	gold quality
colonic epithelium	UBERON:0000397	83.13	gold quality
sural nerve	UBERON:0015488	81.14	gold quality
calcaneal tendon	UBERON:0003701	77.93	gold quality
bone marrow cell	CL:0002092	75.23	gold quality
adrenal tissue	UBERON:0018303	74.74	gold quality
spleen	UBERON:0002106	69.66	gold quality
apex of heart	UBERON:0002098	69.02	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.54	gold quality
right atrium auricular region	UBERON:0006631	66.54	gold quality
cardiac atrium	UBERON:0002081	65.51	gold quality
tonsil	UBERON:0002372	63.82	gold quality
heart left ventricle	UBERON:0002084	63.80	gold quality
uterine cervix	UBERON:0000002	63.19	gold quality
left coronary artery	UBERON:0001626	63.18	gold quality
adrenal gland	UBERON:0002369	62.88	gold quality
heart	UBERON:0000948	62.75	gold quality
cardiac ventricle	UBERON:0002082	62.67	gold quality
tendon	UBERON:0000043	62.56	gold quality
corpus callosum	UBERON:0002336	62.53	gold quality
omental fat pad	UBERON:0010414	62.51	gold quality
peritoneum	UBERON:0002358	62.42	gold quality
popliteal artery	UBERON:0002250	62.31	gold quality
tibial artery	UBERON:0007610	62.28	gold quality
tibial nerve	UBERON:0001323	62.12	gold quality
ventricular zone	UBERON:0003053	61.92	gold quality
left adrenal gland cortex	UBERON:0035825	61.89	gold quality
left adrenal gland	UBERON:0001234	61.37	gold quality
cortical plate	UBERON:0005343	61.20	gold quality
ganglionic eminence	UBERON:0004023	61.16	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-MTAB-11268	no	784.44
E-ANND-3	no	0.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.