TTTY12

Summary

TTTY12 (testis expressed transcript, Y-linked 12, HGNC:18493) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18493
Approved symbol	TTTY12
Name	testis expressed transcript, Y-linked 12
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	TTY11, NCRNA00135
Ensembl gene	ENSG00000237048
Ensembl biotype	lncRNA
Entrez	83867
RNAcentral	URS00022AE745 — lncRNA, 1027 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000413466, ENST00000651670, ENST00000653671, ENST00000664089, ENST00000755458

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413466 — 3 exons

Exon	Start	End
ENSE00001702273	7809861	7810683
ENSE00001793150	7804924	7805079
ENSE00003856234	7803996	7804062

Expression profiles

Bgee: expression breadth broad, 42 present calls, max score 81.13.

Top tissues by expression

181 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.13	gold quality
tibialis anterior	UBERON:0001385	68.84	silver quality
pancreatic ductal cell	CL:0002079	67.13	silver quality
sperm	CL:0000019	66.20	gold quality
ileal mucosa	UBERON:0000331	59.58	silver quality
gastrocnemius	UBERON:0001388	58.22	silver quality
deltoid	UBERON:0001476	57.21	silver quality
monocyte	CL:0000576	56.35	gold quality
epithelial cell of pancreas	CL:0000083	55.51	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
right testis	UBERON:0004534	52.49	gold quality
left testis	UBERON:0004533	52.20	gold quality
testis	UBERON:0000473	51.50	gold quality
myocardium	UBERON:0002349	50.25	gold quality
muscle layer of sigmoid colon	UBERON:0035805	49.29	gold quality
left adrenal gland	UBERON:0001234	48.07	gold quality
quadriceps femoris	UBERON:0001377	47.55	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.14	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
prefrontal cortex	UBERON:0000451	46.84	gold quality
metanephros	UBERON:0000081	46.07	gold quality
skin of leg	UBERON:0001511	46.02	gold quality
tibial artery	UBERON:0007610	45.74	gold quality
vastus lateralis	UBERON:0001379	45.40	gold quality
adult mammalian kidney	UBERON:0000082	44.98	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	44.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.