TTTY18

Summary

TTTY18 (testis expressed transcript, Y-linked 18, HGNC:18842) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18842
Approved symbol	TTTY18
Name	testis expressed transcript, Y-linked 18
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00143
Ensembl gene	ENSG00000233699
Ensembl biotype	lncRNA
Entrez	252950
RNAcentral	URS000050BE5C — lncRNA, 221 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000438677, ENST00000843012, ENST00000843013, ENST00000843014, ENST00000843015, ENST00000843016, ENST00000843017, ENST00000843018, ENST00000843019, ENST00000843020, ENST00000843021, ENST00000843022

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438677 — 7 exons

Exon	Start	End
ENSE00001765620	8682594	8683432
ENSE00003844140	8686683	8686737
ENSE00003845533	8683721	8683939
ENSE00003846293	8689071	8689155
ENSE00003847685	8694448	8694525
ENSE00003849403	8693758	8693963
ENSE00003850759	8700818	8700977

Expression profiles

Bgee: expression breadth broad, 38 present calls, max score 96.12.

Top tissues by expression

38 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.12	gold quality
mucosa of transverse colon	UBERON:0004991	50.30	gold quality
left testis	UBERON:0004533	47.68	gold quality
islet of Langerhans	UBERON:0000006	47.45	silver quality
testis	UBERON:0000473	47.24	gold quality
right testis	UBERON:0004534	46.66	gold quality
muscle of leg	UBERON:0001383	46.53	gold quality
heart left ventricle	UBERON:0002084	46.30	silver quality
body of stomach	UBERON:0001161	45.09	gold quality
tibial artery	UBERON:0007610	44.12	gold quality
hypothalamus	UBERON:0001898	43.94	gold quality
muscle layer of sigmoid colon	UBERON:0035805	43.47	silver quality
subcutaneous adipose tissue	UBERON:0002190	42.63	silver quality
prefrontal cortex	UBERON:0000451	42.44	silver quality
colon	UBERON:0001155	42.40	silver quality
transverse colon	UBERON:0001157	42.19	silver quality
gastrocnemius	UBERON:0001388	41.58	gold quality
tibial nerve	UBERON:0001323	41.49	silver quality
lower esophagus muscularis layer	UBERON:0035833	41.48	silver quality
esophagus mucosa	UBERON:0002469	41.41	silver quality
rectum	UBERON:0001052	41.29	silver quality
skin of abdomen	UBERON:0001416	40.83	silver quality
skin of leg	UBERON:0001511	40.41	silver quality
right atrium auricular region	UBERON:0006631	40.40	silver quality
Brodmann (1909) area 9	UBERON:0013540	40.31	silver quality
putamen	UBERON:0001874	40.23	silver quality
thoracic mammary gland	UBERON:0005200	40.14	silver quality
substantia nigra	UBERON:0002038	40.11	silver quality
omental fat pad	UBERON:0010414	39.92	silver quality
amygdala	UBERON:0001876	38.54	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.