TTTY22

Summary

TTTY22 (testis expressed transcript, Y-linked 22, HGNC:18846) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18846
Approved symbol	TTTY22
Name	testis expressed transcript, Y-linked 22
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00147
Ensembl gene	ENSG00000224075
Ensembl biotype	lncRNA
Entrez	252954
RNAcentral	URS00004EFFB1 — lncRNA, 427 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000445253, ENST00000650665

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000445253 — 5 exons

Exon	Start	End
ENSE00001593910	9813200	9813245
ENSE00001699801	9810071	9810109
ENSE00001742365	9804774	9804885
ENSE00001763553	9809311	9809385
ENSE00001803533	9801153	9801307

Expression profiles

Bgee: expression breadth broad, 37 present calls, max score 79.58.

Top tissues by expression

37 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.58	silver quality
monocyte	CL:0000576	53.42	gold quality
minor salivary gland	UBERON:0001830	52.74	gold quality
islet of Langerhans	UBERON:0000006	50.22	gold quality
blood	UBERON:0000178	48.91	silver quality
subcutaneous adipose tissue	UBERON:0002190	47.67	gold quality
urinary bladder	UBERON:0001255	46.12	silver quality
transverse colon	UBERON:0001157	45.33	gold quality
thoracic mammary gland	UBERON:0005200	44.02	gold quality
ascending aorta	UBERON:0001496	43.88	silver quality
amygdala	UBERON:0001876	43.53	gold quality
right atrium auricular region	UBERON:0006631	43.48	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.13	gold quality
tibial nerve	UBERON:0001323	42.84	gold quality
adenohypophysis	UBERON:0002196	42.67	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	42.05	silver quality
skin of abdomen	UBERON:0001416	42.03	gold quality
cerebral cortex	UBERON:0000956	41.29	silver quality
anterior cingulate cortex	UBERON:0009835	41.10	silver quality
esophagus mucosa	UBERON:0002469	40.89	silver quality
substantia nigra	UBERON:0002038	40.81	silver quality
skin of leg	UBERON:0001511	40.51	gold quality
thyroid gland	UBERON:0002046	40.41	silver quality
multicellular organism	UBERON:0000468	40.37	gold quality
frontal cortex	UBERON:0001870	40.32	silver quality
right frontal lobe	UBERON:0002810	40.06	silver quality
nucleus accumbens	UBERON:0001882	39.88	silver quality
omental fat pad	UBERON:0010414	39.27	silver quality
caudate nucleus	UBERON:0001873	39.16	silver quality
hypothalamus	UBERON:0001898	39.15	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.