TTTY2B

Summary

TTTY2B (testis expressed transcript, Y-linked 2B, HGNC:37982) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37982
Approved symbol	TTTY2B
Name	testis expressed transcript, Y-linked 2B
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000212856
Ensembl biotype	lncRNA
Entrez	100101117
RNAcentral	URS0000759DC4 — lncRNA, 1633 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000450591, ENST00000651733, ENST00000735422, ENST00000735423, ENST00000735424, ENST00000735425, ENST00000735426, ENST00000735427, ENST00000735428, ENST00000735429, ENST00000735430, ENST00000735431, ENST00000735432, ENST00000735433

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450591 — 7 exons

Exon	Start	End
ENSE00001608925	6419765	6419851
ENSE00001661659	6412223	6412371
ENSE00001697617	6406244	6406923
ENSE00001710562	6408147	6408344
ENSE00001712140	6408465	6408543
ENSE00001713628	6422328	6424145
ENSE00001718232	6411374	6411530

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 83.11.

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.11	silver quality
gall bladder	UBERON:0002110	74.65	gold quality
muscle layer of sigmoid colon	UBERON:0035805	56.73	gold quality
mucosa of transverse colon	UBERON:0004991	56.64	gold quality
transverse colon	UBERON:0001157	56.61	gold quality
rectum	UBERON:0001052	56.58	gold quality
colon	UBERON:0001155	56.24	gold quality
intestine	UBERON:0000160	54.11	gold quality
saliva-secreting gland	UBERON:0001044	51.00	gold quality
minor salivary gland	UBERON:0001830	50.68	gold quality
small intestine	UBERON:0002108	50.30	gold quality
right testis	UBERON:0004534	50.20	gold quality
islet of Langerhans	UBERON:0000006	50.04	gold quality
small intestine Peyer’s patch	UBERON:0003454	49.64	gold quality
duodenum	UBERON:0002114	49.60	gold quality
left testis	UBERON:0004533	49.38	gold quality
testis	UBERON:0000473	49.25	gold quality
right lobe of liver	UBERON:0001114	48.25	gold quality
liver	UBERON:0002107	48.11	silver quality
body of pancreas	UBERON:0001150	47.95	gold quality
skin of leg	UBERON:0001511	46.51	gold quality
blood	UBERON:0000178	46.15	gold quality
skin of abdomen	UBERON:0001416	44.92	gold quality
left adrenal gland	UBERON:0001234	44.79	gold quality
left adrenal gland cortex	UBERON:0035825	43.57	gold quality
hypothalamus	UBERON:0001898	43.38	gold quality
tibial nerve	UBERON:0001323	43.22	gold quality
upper lobe of left lung	UBERON:0008952	41.63	silver quality
stomach	UBERON:0000945	41.42	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.18	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.