TTTY4C

Summary

TTTY4C (testis expressed transcript, Y-linked 4C, HGNC:31892) is a long non-coding RNA gene on chromosome Yq11.23.

There are three copies of this gene on chromosome Y. This record represents the most telomeric copy, which is within the P1 palindrome.

Source: NCBI Gene 474150 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31892
Approved symbol	TTTY4C
Name	testis expressed transcript, Y-linked 4C
Location	Yq11.23
Locus type	RNA, long non-coding
Status	Approved
Aliases	LINC00125
Ensembl gene	ENSG00000228296
Ensembl biotype	lncRNA
Entrez	474150
RNAcentral	URS000060599D — lncRNA, 1346 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000456123

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456123 — 4 exons

Exon	Start	End
ENSE00001613955	25099732	25099892
ENSE00001658199	25070734	25070841
ENSE00001702789	25063083	25064083
ENSE00001793058	25072646	25072721

Expression profiles

Bgee: expression breadth broad, 12 present calls, max score 54.62.

Top tissues by expression

12 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
metanephros cortex	UBERON:0010533	54.62	gold quality
kidney	UBERON:0002113	53.79	gold quality
cortex of kidney	UBERON:0001225	53.35	gold quality
adult mammalian kidney	UBERON:0000082	52.53	gold quality
right lobe of liver	UBERON:0001114	50.53	silver quality
islet of Langerhans	UBERON:0000006	48.29	gold quality
body of pancreas	UBERON:0001150	47.30	gold quality
body of stomach	UBERON:0001161	42.86	silver quality
intestine	UBERON:0000160	42.85	silver quality
gall bladder	UBERON:0002110	41.44	silver quality
left testis	UBERON:0004533	27.33	silver quality
right testis	UBERON:0004534	26.98	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (2): TTTY4 (ENSG00000226906), TTTY4B (ENSG00000235412)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.