TTTY5

Summary

TTTY5 (testis expressed transcript, Y-linked 5, HGNC:16482) is a long non-coding RNA gene on chromosome Yq11.223.

There is a single copy of this gene on chromosome Y at the center of the P3 palindrome.

Source: NCBI Gene 83863 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16482
Approved symbol	TTTY5
Name	testis expressed transcript, Y-linked 5
Location	Yq11.223
Locus type	RNA, long non-coding
Status	Approved
Aliases	TTY5, LINC00126
Ensembl gene	ENSG00000215560
Ensembl biotype	lncRNA
OMIM	400038
Entrez	83863
RNAcentral	URS000075BD39 — lncRNA, 1576 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000400581

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000400581 — 2 exons

Exon	Start	End
ENSE00001543606	22296798	22297788
ENSE00001543607	22298306	22298876

Expression profiles

Bgee: expression breadth tissue_specific, 8 present calls, max score 44.37.

Top tissues by expression

168 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vermiform appendix	UBERON:0001154	44.37	silver quality
heart left ventricle	UBERON:0002084	44.06	gold quality
upper leg skin	UBERON:0004262	43.81	silver quality
adrenal gland	UBERON:0002369	43.80	gold quality
small intestine	UBERON:0002108	43.68	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
small intestine Peyer’s patch	UBERON:0003454	43.36	silver quality
ventral tegmental area	UBERON:0002691	43.15	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
jejunum	UBERON:0002115	42.54	gold quality
epithelium of nasopharynx	UBERON:0001951	42.47	gold quality
cardiac ventricle	UBERON:0002082	42.47	gold quality
heart	UBERON:0000948	42.30	gold quality
blood	UBERON:0000178	42.09	gold quality
skin of hip	UBERON:0001554	41.96	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	41.86	gold quality
inferior vagus X ganglion	UBERON:0005363	41.51	gold quality
transverse colon	UBERON:0001157	41.49	silver quality
skeletal muscle tissue	UBERON:0001134	41.44	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
prefrontal cortex	UBERON:0000451	41.35	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
biceps brachii	UBERON:0001507	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality
mucosa of paranasal sinus	UBERON:0005030	40.98	gold quality
endometrium	UBERON:0001295	40.72	gold quality
amniotic fluid	UBERON:0000173	40.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.