TTTY8

Summary

TTTY8 (testis expressed transcript, Y-linked 8, HGNC:18489) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18489
Approved symbol	TTTY8
Name	testis expressed transcript, Y-linked 8
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	TTY8, NCRNA00130, LINC00130
Ensembl gene	ENSG00000183385
Ensembl biotype	lncRNA
Entrez	84673
RNAcentral	URS000075ACA0 — lncRNA, 542 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000329684, ENST00000426035, ENST00000849214, ENST00000849215, ENST00000849216, ENST00000849217

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000329684 — 3 exons

Exon	Start	End
ENSE00001693371	9691713	9691917
ENSE00001729545	9693510	9693699
ENSE00004279460	9691069	9691235

Expression profiles

Bgee: expression breadth broad, 73 present calls, max score 62.12.

Top tissues by expression

73 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	62.12	silver quality
endometrium	UBERON:0001295	61.02	silver quality
skeletal muscle tissue	UBERON:0001134	58.63	gold quality
bone marrow	UBERON:0002371	53.76	gold quality
monocyte	CL:0000576	53.09	silver quality
testis	UBERON:0000473	50.38	gold quality
left testis	UBERON:0004533	50.04	gold quality
blood	UBERON:0000178	49.67	silver quality
calcaneal tendon	UBERON:0003701	49.59	silver quality
right testis	UBERON:0004534	49.43	gold quality
liver	UBERON:0002107	48.07	silver quality
muscle of leg	UBERON:0001383	47.96	gold quality
islet of Langerhans	UBERON:0000006	46.88	gold quality
gastrocnemius	UBERON:0001388	46.45	gold quality
body of pancreas	UBERON:0001150	46.06	gold quality
tibial artery	UBERON:0007610	45.85	gold quality
right lobe of liver	UBERON:0001114	45.68	silver quality
prefrontal cortex	UBERON:0000451	45.20	gold quality
multicellular organism	UBERON:0000468	44.27	gold quality
right lobe of thyroid gland	UBERON:0001119	43.99	gold quality
myometrium	UBERON:0001296	43.63	gold quality
heart left ventricle	UBERON:0002084	43.51	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.24	silver quality
substantia nigra	UBERON:0002038	43.18	gold quality
left coronary artery	UBERON:0001626	42.63	gold quality
cerebellar hemisphere	UBERON:0002245	42.54	silver quality
stomach	UBERON:0000945	42.37	silver quality
heart	UBERON:0000948	42.28	silver quality
body of uterus	UBERON:0009853	42.27	silver quality
adult mammalian kidney	UBERON:0000082	42.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.