TTTY8B

Summary

TTTY8B (testis expressed transcript, Y-linked 8B, HGNC:37622) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37622
Approved symbol	TTTY8B
Name	testis expressed transcript, Y-linked 8B
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00217
Ensembl gene	ENSG00000185700
Ensembl biotype	lncRNA
Entrez	100101118
RNAcentral	URS0000759A30 — lncRNA, 533 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000328819, ENST00000455570, ENST00000736416, ENST00000736417, ENST00000736418

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000328819 — 3 exons

Exon	Start	End
ENSE00001598872	6471031	6471220
ENSE00001632371	6472813	6473017
ENSE00004069737	6473495	6473655

Expression profiles

Bgee: expression breadth broad, 67 present calls, max score 79.89.

Top tissues by expression

67 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	79.89	gold quality
calcaneal tendon	UBERON:0003701	56.07	gold quality
monocyte	CL:0000576	52.08	silver quality
myometrium	UBERON:0001296	51.89	gold quality
muscle of leg	UBERON:0001383	51.44	gold quality
blood	UBERON:0000178	50.81	silver quality
left testis	UBERON:0004533	50.50	gold quality
testis	UBERON:0000473	49.92	gold quality
gastrocnemius	UBERON:0001388	48.25	gold quality
substantia nigra	UBERON:0002038	48.10	gold quality
corpus callosum	UBERON:0002336	47.33	silver quality
prefrontal cortex	UBERON:0000451	46.93	silver quality
cortex of kidney	UBERON:0001225	46.83	silver quality
islet of Langerhans	UBERON:0000006	45.64	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.55	gold quality
right testis	UBERON:0004534	45.28	gold quality
multicellular organism	UBERON:0000468	45.07	gold quality
right lobe of thyroid gland	UBERON:0001119	44.35	silver quality
body of uterus	UBERON:0009853	44.19	gold quality
right atrium auricular region	UBERON:0006631	44.07	gold quality
tibial nerve	UBERON:0001323	44.03	silver quality
liver	UBERON:0002107	43.61	silver quality
stomach	UBERON:0000945	43.59	silver quality
cerebellar cortex	UBERON:0002129	43.37	silver quality
tibial artery	UBERON:0007610	43.27	silver quality
heart left ventricle	UBERON:0002084	43.25	silver quality
ectocervix	UBERON:0012249	43.17	gold quality
thoracic mammary gland	UBERON:0005200	43.02	gold quality
adrenal gland	UBERON:0002369	42.73	silver quality
lower esophagus muscularis layer	UBERON:0035833	42.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.