TTTY9B

Summary

TTTY9B (testis expressed transcript, Y-linked 9B, HGNC:32425) is a long non-coding RNA gene on chromosome Yq11.222.

This gene is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region (P4) on chromosome Y. This record represents the more centromeric copy.

Source: NCBI Gene 425057 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32425
Approved symbol	TTTY9B
Name	testis expressed transcript, Y-linked 9B
Location	Yq11.222
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00132
Ensembl gene	ENSG00000131007
Ensembl biotype	lncRNA
Entrez	425057
RNAcentral	URS00001CF151 — lncRNA, 1637 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000433794, ENST00000545582, ENST00000776413

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433794 — 5 exons

Exon	Start	End
ENSE00001668181	18590380	18590521
ENSE00001757235	18588131	18588244
ENSE00003505404	18588606	18588706
ENSE00003733932	18587412	18587548
ENSE00003752489	18581206	18582348

Expression profiles

Bgee: expression breadth broad, 58 present calls, max score 64.15.

Top tissues by expression

58 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortex of kidney	UBERON:0001225	64.15	gold quality
metanephros cortex	UBERON:0010533	58.00	gold quality
kidney	UBERON:0002113	56.73	gold quality
liver	UBERON:0002107	55.88	silver quality
adult mammalian kidney	UBERON:0000082	54.11	gold quality
monocyte	CL:0000576	51.80	silver quality
endometrium	UBERON:0001295	51.24	silver quality
testis	UBERON:0000473	50.52	gold quality
left testis	UBERON:0004533	50.19	gold quality
left coronary artery	UBERON:0001626	49.65	gold quality
right testis	UBERON:0004534	48.81	gold quality
blood	UBERON:0000178	48.71	silver quality
prefrontal cortex	UBERON:0000451	48.54	silver quality
subcutaneous adipose tissue	UBERON:0002190	48.43	gold quality
lymph node	UBERON:0000029	48.21	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	47.18	gold quality
thoracic mammary gland	UBERON:0005200	47.10	gold quality
omental fat pad	UBERON:0010414	47.04	gold quality
transverse colon	UBERON:0001157	46.59	gold quality
muscle of leg	UBERON:0001383	45.88	gold quality
popliteal artery	UBERON:0002250	45.74	gold quality
heart left ventricle	UBERON:0002084	45.66	gold quality
tibial artery	UBERON:0007610	45.61	gold quality
placenta	UBERON:0001987	45.39	silver quality
islet of Langerhans	UBERON:0000006	45.35	silver quality
saliva-secreting gland	UBERON:0001044	45.27	silver quality
right coronary artery	UBERON:0001625	45.25	gold quality
skin of abdomen	UBERON:0001416	44.84	gold quality
vermiform appendix	UBERON:0001154	44.16	silver quality
gastrocnemius	UBERON:0001388	44.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): TTTY9A (ENSG00000290716)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.