TUBA1B-AS1

Summary

TUBA1B-AS1 (TUBA1B antisense RNA 1, HGNC:56356) is a long non-coding RNA gene on chromosome 12q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56356
Approved symbol	TUBA1B-AS1
Name	TUBA1B antisense RNA 1
Location	12q13.12
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-386G11.10
Ensembl gene	ENSG00000258017
Ensembl biotype	lncRNA
Entrez	105369760
RNAcentral	URS00026A25B5 — lncRNA, 421 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000547387, ENST00000547712, ENST00000548149, ENST00000551496, ENST00000552893, ENST00000656133, ENST00000664160, ENST00000665211, ENST00000667827, ENST00000687351, ENST00000811789, ENST00000811790, ENST00000811791

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000547387 — 2 exons

Exon	Start	End
ENSE00002349893	49131320	49131362
ENSE00002376595	49128011	49128864

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 99.80.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	99.80	gold quality
primary visual cortex	UBERON:0002436	99.73	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	99.54	gold quality
ventricular zone	UBERON:0003053	99.40	gold quality
mucosa of transverse colon	UBERON:0004991	99.31	gold quality
Brodmann (1909) area 9	UBERON:0013540	99.23	gold quality
lower esophagus mucosa	UBERON:0035834	99.19	gold quality
prefrontal cortex	UBERON:0000451	99.18	gold quality
temporal lobe	UBERON:0001871	99.06	gold quality
amygdala	UBERON:0001876	99.05	gold quality
adenohypophysis	UBERON:0002196	98.75	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	98.67	gold quality
anterior cingulate cortex	UBERON:0009835	98.67	gold quality
substantia nigra	UBERON:0002038	98.53	gold quality
hypothalamus	UBERON:0001898	98.51	gold quality
cerebral cortex	UBERON:0000956	98.27	gold quality
frontal cortex	UBERON:0001870	98.26	gold quality
Ammon’s horn	UBERON:0001954	98.21	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	98.06	gold quality
right hemisphere of cerebellum	UBERON:0014890	98.02	gold quality
colonic epithelium	UBERON:0000397	97.67	gold quality
stromal cell of endometrium	CL:0002255	97.60	gold quality
pituitary gland	UBERON:0000007	97.47	gold quality
calcaneal tendon	UBERON:0003701	97.44	gold quality
right frontal lobe	UBERON:0002810	97.28	gold quality
brain	UBERON:0000955	97.20	gold quality
left testis	UBERON:0004533	96.86	gold quality
right testis	UBERON:0004534	96.71	gold quality
sural nerve	UBERON:0015488	96.48	gold quality
caudate nucleus	UBERON:0001873	96.19	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	5833.48
E-ANND-3	no	1.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.