TWF2-DT

Summary

TWF2-DT (TWF2 divergent transcript, HGNC:55619) is a long non-coding RNA gene on chromosome 3p21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55619
Approved symbol	TWF2-DT
Name	TWF2 divergent transcript
Location	3p21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243224
Ensembl biotype	lncRNA
Entrez	101929054
RNAcentral	URS0000A76425 — lncRNA, 1161 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000464958, ENST00000483834, ENST00000816612

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000464958 — 2 exons

Exon	Start	End
ENSE00004219563	52240178	52241122
ENSE00004219564	52239251	52239435

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 96.94.

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.94	silver quality
sperm	CL:0000019	85.29	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	80.65	gold quality
oocyte	CL:0000023	78.17	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	77.81	gold quality
vena cava	UBERON:0004087	74.62	silver quality
epithelium of nasopharynx	UBERON:0001951	74.61	gold quality
quadriceps femoris	UBERON:0001377	74.43	gold quality
vastus lateralis	UBERON:0001379	74.32	gold quality
ventral tegmental area	UBERON:0002691	74.25	silver quality
superficial temporal artery	UBERON:0001614	73.15	gold quality
pons	UBERON:0000988	72.63	silver quality
saphenous vein	UBERON:0007318	72.62	silver quality
dorsal root ganglion	UBERON:0000044	72.56	silver quality
pharyngeal mucosa	UBERON:0000355	72.54	silver quality
superior surface of tongue	UBERON:0007371	72.48	silver quality
tongue	UBERON:0001723	72.39	silver quality
thymus	UBERON:0002370	72.28	silver quality
cerebellar vermis	UBERON:0004720	72.06	silver quality
nipple	UBERON:0002030	71.92	silver quality
lateral globus pallidus	UBERON:0002476	71.91	gold quality
substantia nigra pars reticulata	UBERON:0001966	71.80	silver quality
secondary oocyte	CL:0000655	71.73	gold quality
pericardium	UBERON:0002407	71.73	gold quality
lateral nuclear group of thalamus	UBERON:0002736	71.59	gold quality
superior vestibular nucleus	UBERON:0007227	71.59	silver quality
trigeminal ganglion	UBERON:0001675	71.50	silver quality
substantia nigra pars compacta	UBERON:0001965	71.11	gold quality
mucosa of paranasal sinus	UBERON:0005030	71.09	gold quality
endothelial cell	CL:0000115	70.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.