TWSG1-DT

Summary

TWSG1-DT (TWSG1 divergent transcript, HGNC:55329) is a long non-coding RNA gene on chromosome 18p11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55329
Approved symbol	TWSG1-DT
Name	TWSG1 divergent transcript
Location	18p11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264964
Ensembl biotype	lncRNA
Entrez	102724397
RNAcentral	URS00026A1A94 — lncRNA, 1014 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000584509, ENST00000822310, ENST00000822311, ENST00000822312, ENST00000822313, ENST00000822314, ENST00000822315, ENST00000822316, ENST00000822317, ENST00000822318, ENST00000822319, ENST00000822320, ENST00000822321, ENST00000822322, ENST00000822323, ENST00000822324, ENST00000822325, ENST00000822326, ENST00000822327, ENST00000822328, ENST00000822329, ENST00000822330

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000584509 — 3 exons

Exon	Start	End
ENSE00002684888	9334137	9334445
ENSE00002694612	9322062	9322152
ENSE00002725228	9310522	9315263

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 77.93.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.93	silver quality
ventricular zone	UBERON:0003053	60.68	gold quality
monocyte	CL:0000576	59.75	gold quality
cortical plate	UBERON:0005343	57.54	silver quality
ganglionic eminence	UBERON:0004023	57.27	silver quality
skeletal muscle tissue	UBERON:0001134	55.12	silver quality
hindlimb stylopod muscle	UBERON:0004252	54.96	silver quality
stromal cell of endometrium	CL:0002255	54.78	silver quality
popliteal artery	UBERON:0002250	52.78	gold quality
tibial artery	UBERON:0007610	52.73	gold quality
bone marrow	UBERON:0002371	51.27	silver quality
muscle tissue	UBERON:0002385	50.66	gold quality
descending thoracic aorta	UBERON:0002345	50.50	gold quality
urinary bladder	UBERON:0001255	50.42	gold quality
right coronary artery	UBERON:0001625	50.28	gold quality
prefrontal cortex	UBERON:0000451	50.03	silver quality
lymph node	UBERON:0000029	49.72	silver quality
blood	UBERON:0000178	49.67	silver quality
thoracic aorta	UBERON:0001515	49.43	gold quality
ascending aorta	UBERON:0001496	49.29	gold quality
lower esophagus	UBERON:0013473	48.60	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.56	gold quality
mucosa of transverse colon	UBERON:0004991	47.99	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	47.92	gold quality
myometrium	UBERON:0001296	47.81	gold quality
left coronary artery	UBERON:0001626	47.75	gold quality
islet of Langerhans	UBERON:0000006	47.27	silver quality
duodenum	UBERON:0002114	47.16	silver quality
endometrium	UBERON:0001295	47.13	silver quality
gall bladder	UBERON:0002110	47.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.