UBL7-DT

Summary

UBL7-DT (UBL7 divergent transcript, HGNC:48614) is a long non-coding RNA gene on chromosome 15q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48614
Approved symbol	UBL7-DT
Name	UBL7 divergent transcript
Location	15q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247240
Ensembl biotype	lncRNA
Entrez	440288
RNAcentral	URS000075E2C8 — lncRNA, 1690 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 103 — 103 lncRNA

ENST00000499217, ENST00000562869, ENST00000564137, ENST00000564621, ENST00000567286, ENST00000568853, ENST00000657781, ENST00000659591, ENST00000664892, ENST00000666989, ENST00000670462, ENST00000689930, ENST00000691484, ENST00000693152, ENST00000701606, ENST00000701687, ENST00000836086, ENST00000836087, ENST00000836088, ENST00000836089, ENST00000836090, ENST00000836091, ENST00000836092, ENST00000836093, ENST00000836094, ENST00000836095, ENST00000836096, ENST00000836097, ENST00000836098, ENST00000836099, ENST00000836100, ENST00000836101, ENST00000836102, ENST00000836103, ENST00000836104, ENST00000836105, ENST00000836106, ENST00000836107, ENST00000836108, ENST00000836109, ENST00000836110, ENST00000836111, ENST00000836112, ENST00000836113, ENST00000836114, ENST00000836115, ENST00000836116, ENST00000836117, ENST00000836118, ENST00000836119, ENST00000836120, ENST00000836121, ENST00000836122, ENST00000836123, ENST00000836124, ENST00000836125, ENST00000836126, ENST00000836127, ENST00000836128, ENST00000836129, ENST00000836130, ENST00000836131, ENST00000836132, ENST00000836133, ENST00000836134, ENST00000836135, ENST00000836136, ENST00000836137, ENST00000836138, ENST00000836139, ENST00000836140, ENST00000836141, ENST00000836142, ENST00000836143, ENST00000836144, ENST00000836145, ENST00000836146, ENST00000836147, ENST00000836148, ENST00000836149, ENST00000836150, ENST00000836151, ENST00000836152, ENST00000836153, ENST00000836154, ENST00000836155, ENST00000836156, ENST00000836157, ENST00000836158, ENST00000836159, ENST00000836160, ENST00000836161, ENST00000836162, ENST00000836163, ENST00000836164, ENST00000836165, ENST00000836166, ENST00000836167, ENST00000836168, ENST00000836169, ENST00000836170, ENST00000836171, ENST00000836172

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499217 — 4 exons

Exon	Start	End
ENSE00001753720	74466036	74466130
ENSE00001971221	74479060	74479278
ENSE00004255202	74481051	74481309
ENSE00004255235	74461238	74462031

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 85.50.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.8970 / max 110.1213, expressed in 1474 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
147697	4.4265	1436
147698	0.2436	120
147696	0.2268	106

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.50	gold quality
ventricular zone	UBERON:0003053	77.17	gold quality
bone marrow cell	CL:0002092	76.47	gold quality
bone marrow	UBERON:0002371	76.11	gold quality
lymph node	UBERON:0000029	75.92	gold quality
ganglionic eminence	UBERON:0004023	75.65	gold quality
leukocyte	CL:0000738	75.54	gold quality
monocyte	CL:0000576	75.53	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.53	silver quality
granulocyte	CL:0000094	74.77	gold quality
cortical plate	UBERON:0005343	73.68	gold quality
placenta	UBERON:0001987	73.49	gold quality
gastrocnemius	UBERON:0001388	72.88	gold quality
blood	UBERON:0000178	72.78	gold quality
muscle of leg	UBERON:0001383	72.50	gold quality
tonsil	UBERON:0002372	72.07	gold quality
rectum	UBERON:0001052	72.02	gold quality
stromal cell of endometrium	CL:0002255	71.31	gold quality
testis	UBERON:0000473	71.26	gold quality
muscle tissue	UBERON:0002385	71.19	gold quality
mucosa of transverse colon	UBERON:0004991	70.81	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.75	gold quality
skin of leg	UBERON:0001511	70.69	gold quality
duodenum	UBERON:0002114	70.68	gold quality
skeletal muscle tissue	UBERON:0001134	70.62	gold quality
zone of skin	UBERON:0000014	70.57	gold quality
islet of Langerhans	UBERON:0000006	70.52	gold quality
skin of abdomen	UBERON:0001416	70.29	gold quality
spleen	UBERON:0002106	70.23	gold quality
gall bladder	UBERON:0002110	70.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.17

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation. (PMID:35313638)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.