UBR5-DT

Summary

UBR5-DT (UBR5 divergent transcript, HGNC:51661) is a long non-coding RNA gene on chromosome 8q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51661
Approved symbol	UBR5-DT
Name	UBR5 divergent transcript
Location	8q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246263
Ensembl biotype	lncRNA
Entrez	101927221
RNAcentral	URS00007E3683 — lncRNA, 743 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000499653, ENST00000520820, ENST00000667853, ENST00000747751, ENST00000747752, ENST00000747753

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499653 — 2 exons

Exon	Start	End
ENSE00001962645	102243609	102244121
ENSE00001981442	102251799	102253333

Expression profiles

Bgee: expression breadth ubiquitous, 203 present calls, max score 86.11.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.0283 / max 224.4358, expressed in 1118 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
90041	2.4298	906
90040	1.5985	522

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oocyte	CL:0000023	86.11	gold quality
blood	UBERON:0000178	83.75	gold quality
secondary oocyte	CL:0000655	82.41	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.92	gold quality
monocyte	CL:0000576	79.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.75	gold quality
leukocyte	CL:0000738	79.40	gold quality
oviduct epithelium	UBERON:0004804	77.63	gold quality
bone marrow cell	CL:0002092	77.62	gold quality
bone marrow	UBERON:0002371	77.14	gold quality
spleen	UBERON:0002106	76.49	gold quality
mucosa of transverse colon	UBERON:0004991	75.04	gold quality
bronchial epithelial cell	CL:0002328	74.61	gold quality
granulocyte	CL:0000094	73.44	gold quality
bronchus	UBERON:0002185	73.30	gold quality
colonic epithelium	UBERON:0000397	73.25	gold quality
epithelium of nasopharynx	UBERON:0001951	73.10	gold quality
right lobe of thyroid gland	UBERON:0001119	72.32	gold quality
thyroid gland	UBERON:0002046	72.17	gold quality
left lobe of thyroid gland	UBERON:0001120	71.95	gold quality
adenohypophysis	UBERON:0002196	71.79	gold quality
right uterine tube	UBERON:0001302	71.75	gold quality
nucleus accumbens	UBERON:0001882	71.60	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.43	gold quality
right lung	UBERON:0002167	71.34	gold quality
gastrocnemius	UBERON:0001388	71.30	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.21	gold quality
muscle of leg	UBERON:0001383	70.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.52	gold quality
putamen	UBERON:0001874	70.51	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.