UMLILO

Summary

UMLILO (upstream master lncRNA of the inflammatory chemokine locus, HGNC:51824) is a long non-coding RNA gene on chromosome 4q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51824
Approved symbol	UMLILO
Name	upstream master lncRNA of the inflammatory chemokine locus
Location	4q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228277
Ensembl biotype	lncRNA
Entrez	114515515
RNAcentral	URS0002338648 — lncRNA, 530 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000436089, ENST00000821866, ENST00000821867, ENST00000821868, ENST00000821869, ENST00000821870

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436089 — 3 exons

Exon	Start	End
ENSE00001641678	73710302	73710395
ENSE00001754580	73714166	73714527
ENSE00001792922	73713337	73713455

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 93.77.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0645 / max 20.6201, expressed in 16 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
48167	0.0645	16

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.77	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.57	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	55.77	gold quality
vermiform appendix	UBERON:0001154	54.06	gold quality
monocyte	CL:0000576	53.60	gold quality
cortex of kidney	UBERON:0001225	50.60	gold quality
lung	UBERON:0002048	50.31	gold quality
blood	UBERON:0000178	50.15	gold quality
right lobe of liver	UBERON:0001114	47.48	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	46.94	gold quality
body of stomach	UBERON:0001161	46.28	gold quality
minor salivary gland	UBERON:0001830	46.20	gold quality
granulocyte	CL:0000094	45.79	silver quality
lower esophagus muscularis layer	UBERON:0035833	44.81	silver quality
tibial nerve	UBERON:0001323	44.50	silver quality
omental fat pad	UBERON:0010414	44.34	gold quality
ascending aorta	UBERON:0001496	43.95	silver quality
esophagus mucosa	UBERON:0002469	43.72	gold quality
muscle layer of sigmoid colon	UBERON:0035805	43.20	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.41	silver quality
body of pancreas	UBERON:0001150	42.17	silver quality
tibial artery	UBERON:0007610	41.77	silver quality
amygdala	UBERON:0001876	41.03	silver quality
zone of skin	UBERON:0000014	40.46	silver quality
skin of abdomen	UBERON:0001416	40.15	silver quality
rectum	UBERON:0001052	39.81	silver quality
adult mammalian kidney	UBERON:0000082	39.65	silver quality
transverse colon	UBERON:0001157	39.35	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	39.13	silver quality
skin of leg	UBERON:0001511	39.01	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.