UNC5C-AS1

Summary

UNC5C-AS1 (UNC5C antisense RNA 1, HGNC:55246) is a long non-coding RNA gene on chromosome 4q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55246
Approved symbol	UNC5C-AS1
Name	UNC5C antisense RNA 1
Location	4q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271474
Ensembl biotype	lncRNA
Entrez	105377335
RNAcentral	URS00026A1F92 — lncRNA, 2996 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000605849, ENST00000778702

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000605849 — 1 exons

Exon	Start	End
ENSE00004148385	95548924	95552457

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 86.70.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5011 / max 22.8407, expressed in 222 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
48968	0.3318	158
48969	0.1693	94

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
endothelial cell	CL:0000115	86.70	gold quality
prefrontal cortex	UBERON:0000451	73.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.74	gold quality
frontal cortex	UBERON:0001870	69.54	gold quality
popliteal artery	UBERON:0002250	69.49	gold quality
tibial artery	UBERON:0007610	69.46	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.26	gold quality
left lobe of thyroid gland	UBERON:0001120	69.18	gold quality
medial globus pallidus	UBERON:0002477	69.15	gold quality
neocortex	UBERON:0001950	69.11	gold quality
right lobe of thyroid gland	UBERON:0001119	69.08	gold quality
amygdala	UBERON:0001876	68.99	gold quality
spinal cord	UBERON:0002240	68.90	gold quality
thyroid gland	UBERON:0002046	68.87	gold quality
right coronary artery	UBERON:0001625	68.64	gold quality
Ammon’s horn	UBERON:0001954	68.35	gold quality
right frontal lobe	UBERON:0002810	68.10	gold quality
anterior cingulate cortex	UBERON:0009835	67.96	gold quality
cerebral cortex	UBERON:0000956	67.87	gold quality
left coronary artery	UBERON:0001626	67.52	gold quality
primary visual cortex	UBERON:0002436	66.66	gold quality
hypothalamus	UBERON:0001898	66.59	gold quality
aorta	UBERON:0000947	66.46	gold quality
cortical plate	UBERON:0005343	66.16	gold quality
coronary artery	UBERON:0001621	66.13	gold quality
nucleus accumbens	UBERON:0001882	65.68	gold quality
putamen	UBERON:0001874	65.34	gold quality
Brodmann (1909) area 23	UBERON:0013554	65.17	gold quality
left adrenal gland	UBERON:0001234	64.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.