URB1-DT

Summary

URB1-DT (URB1 divergent transcript, HGNC:23128) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23128
Approved symbol	URB1-DT
Name	URB1 divergent transcript
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	PRED84, MGC14136
Ensembl gene	ENSG00000256073
Ensembl biotype	lncRNA
Entrez	84996
RNAcentral	URS000075DC51 — lncRNA, 828 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000534991

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000534991 — 1 exons

Exon	Start	End
ENSE00004084358	32393048	32394380

Expression profiles

Bgee: expression breadth ubiquitous, 173 present calls, max score 88.16.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.7893 / max 48.3036, expressed in 1600 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188811	3.7893	1600

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.16	gold quality
corpus epididymis	UBERON:0004359	87.04	gold quality
apex of heart	UBERON:0002098	86.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.31	gold quality
adenohypophysis	UBERON:0002196	83.36	gold quality
hypothalamus	UBERON:0001898	83.30	gold quality
gastrocnemius	UBERON:0001388	83.13	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.03	gold quality
muscle of leg	UBERON:0001383	82.85	gold quality
mucosa of paranasal sinus	UBERON:0005030	82.69	gold quality
pituitary gland	UBERON:0000007	82.67	gold quality
left adrenal gland cortex	UBERON:0035825	82.38	gold quality
upper arm skin	UBERON:0004263	82.36	gold quality
heart left ventricle	UBERON:0002084	82.28	gold quality
left adrenal gland	UBERON:0001234	81.98	gold quality
cardiac ventricle	UBERON:0002082	81.85	gold quality
right adrenal gland	UBERON:0001233	81.58	gold quality
putamen	UBERON:0001874	81.39	gold quality
mucosa of transverse colon	UBERON:0004991	81.27	gold quality
right adrenal gland cortex	UBERON:0035827	81.21	gold quality
adrenal cortex	UBERON:0001235	81.13	gold quality
nucleus accumbens	UBERON:0001882	80.95	gold quality
prefrontal cortex	UBERON:0000451	80.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	80.83	gold quality
amygdala	UBERON:0001876	80.73	gold quality
anterior cingulate cortex	UBERON:0009835	80.68	gold quality
mucosa of stomach	UBERON:0001199	80.35	gold quality
caudate nucleus	UBERON:0001873	80.03	gold quality
bronchial epithelial cell	CL:0002328	79.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.67

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Upregulation of MAPKAPK5-AS1, PXN-AS1 and URB1-AS1 lncRNAs in non-functioning pituitary adenoma. (PMID:37154079)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.