USH2A-AS1

Summary

USH2A-AS1 (USH2A antisense RNA 1, HGNC:40606) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40606
Approved symbol	USH2A-AS1
Name	USH2A antisense RNA 1
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236292
Ensembl biotype	lncRNA
Entrez	105372918
RNAcentral	URS000002B889 — lncRNA, 699 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000420867, ENST00000747930, ENST00000747931

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420867 — 3 exons

Exon	Start	End
ENSE00001668179	216204030	216204366
ENSE00001738921	216195743	216195925
ENSE00001779935	216194051	216194229

Expression profiles

Bgee: expression breadth broad, 21 present calls, max score 91.79.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	91.79	silver quality
bone marrow	UBERON:0002371	91.24	silver quality
spinal cord	UBERON:0002240	90.39	silver quality
kidney	UBERON:0002113	90.07	silver quality
thymus	UBERON:0002370	90.04	silver quality
skeletal muscle tissue	UBERON:0001134	89.07	silver quality
lung	UBERON:0002048	88.87	silver quality
spleen	UBERON:0002106	87.23	silver quality
quadriceps femoris	UBERON:0001377	86.05	gold quality
caudate nucleus	UBERON:0001873	77.64	gold quality
pancreas	UBERON:0001264	77.16	silver quality
cerebellar vermis	UBERON:0004720	76.61	gold quality
frontal cortex	UBERON:0001870	74.25	gold quality
left testis	UBERON:0004533	64.03	gold quality
testis	UBERON:0000473	63.27	gold quality
right testis	UBERON:0004534	61.21	gold quality
multicellular organism	UBERON:0000468	60.20	gold quality
blood	UBERON:0000178	55.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.30	silver quality
tibial nerve	UBERON:0001323	48.46	gold quality
gastrocnemius	UBERON:0001388	45.82	gold quality
amygdala	UBERON:0001876	42.54	silver quality
heart	UBERON:0000948	42.33	silver quality
anterior cingulate cortex	UBERON:0009835	42.02	gold quality
tibial artery	UBERON:0007610	41.78	silver quality
heart left ventricle	UBERON:0002084	41.64	silver quality
prostate gland	UBERON:0002367	41.36	silver quality
right atrium auricular region	UBERON:0006631	40.34	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	38.89	silver quality
ascending aorta	UBERON:0001496	38.43	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.