USH2A-AS2

Summary

USH2A-AS2 (USH2A antisense RNA 2, HGNC:40605) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40605
Approved symbol	USH2A-AS2
Name	USH2A antisense RNA 2
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233620
Ensembl biotype	lncRNA
Entrez	102723833
RNAcentral	URS0000324056 — lncRNA, 461 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000430890, ENST00000442606, ENST00000445619, ENST00000446411, ENST00000796399

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430890 — 3 exons

Exon	Start	End
ENSE00001636522	216072729	216072806
ENSE00001664958	216079073	216079201
ENSE00001696318	216086722	216086905

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 85.41.

Top tissues by expression

62 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	85.41	gold quality
anterior cingulate cortex	UBERON:0009835	84.19	gold quality
cerebellar vermis	UBERON:0004720	81.77	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.07	silver quality
spleen	UBERON:0002106	79.62	silver quality
liver	UBERON:0002107	78.90	silver quality
bone marrow	UBERON:0002371	77.89	silver quality
thymus	UBERON:0002370	77.75	silver quality
left testis	UBERON:0004533	77.54	gold quality
skeletal muscle tissue	UBERON:0001134	77.31	silver quality
testis	UBERON:0000473	76.67	gold quality
right testis	UBERON:0004534	75.21	gold quality
spinal cord	UBERON:0002240	71.81	silver quality
multicellular organism	UBERON:0000468	63.17	gold quality
monocyte	CL:0000576	60.06	gold quality
gall bladder	UBERON:0002110	57.28	gold quality
gastrocnemius	UBERON:0001388	55.97	gold quality
kidney	UBERON:0002113	55.48	gold quality
blood	UBERON:0000178	54.43	gold quality
adult mammalian kidney	UBERON:0000082	54.36	gold quality
Ammon’s horn	UBERON:0001954	53.30	gold quality
tibial artery	UBERON:0007610	49.20	gold quality
body of stomach	UBERON:0001161	49.03	gold quality
pancreas	UBERON:0001264	49.03	silver quality
body of pancreas	UBERON:0001150	48.61	gold quality
caudate nucleus	UBERON:0001873	48.55	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.74	gold quality
heart left ventricle	UBERON:0002084	47.24	gold quality
putamen	UBERON:0001874	47.01	gold quality
amygdala	UBERON:0001876	46.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.