UST-AS1

Summary

UST-AS1 (UST antisense RNA 1, HGNC:40802) is a long non-coding RNA gene on chromosome 6q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40802
Approved symbol	UST-AS1
Name	UST antisense RNA 1
Location	6q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227660
Ensembl biotype	lncRNA
Entrez	100128176
RNAcentral	URS000075E7DD — lncRNA, 2083 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000413845, ENST00000802523

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413845 — 3 exons

Exon	Start	End
ENSE00001639681	148958978	148959041
ENSE00004192162	148964561	148964696
ENSE00004192163	148955628	148956153

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 83.04.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0143 / max 18.9456, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76101	0.0143	3

Top tissues by expression

186 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.04	gold quality
sural nerve	UBERON:0015488	71.90	gold quality
colonic epithelium	UBERON:0000397	71.71	gold quality
adrenal tissue	UBERON:0018303	66.90	gold quality
left testis	UBERON:0004533	63.22	gold quality
testis	UBERON:0000473	61.77	gold quality
right testis	UBERON:0004534	60.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.88	gold quality
lower lobe of lung	UBERON:0008949	56.97	silver quality
calcaneal tendon	UBERON:0003701	55.16	gold quality
skin of hip	UBERON:0001554	52.66	silver quality
ascending aorta	UBERON:0001496	50.97	gold quality
thoracic aorta	UBERON:0001515	50.71	gold quality
adrenal gland	UBERON:0002369	49.66	gold quality
tonsil	UBERON:0002372	48.99	gold quality
tendon	UBERON:0000043	48.68	silver quality
monocyte	CL:0000576	48.46	silver quality
aorta	UBERON:0000947	48.37	gold quality
descending thoracic aorta	UBERON:0002345	48.28	gold quality
corpus callosum	UBERON:0002336	48.07	gold quality
lung	UBERON:0002048	47.17	gold quality
prefrontal cortex	UBERON:0000451	47.04	gold quality
thyroid gland	UBERON:0002046	46.30	gold quality
uterine cervix	UBERON:0000002	46.22	silver quality
ectocervix	UBERON:0012249	46.08	gold quality
tibial artery	UBERON:0007610	46.06	gold quality
popliteal artery	UBERON:0002250	46.04	gold quality
adult organism	UBERON:0007023	45.49	silver quality
left lobe of thyroid gland	UBERON:0001120	45.37	gold quality
left coronary artery	UBERON:0001626	45.05	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.