UST-AS2

Summary

UST-AS2 (UST antisense RNA 2, HGNC:40803) is a long non-coding RNA gene on chromosome 6q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40803
Approved symbol	UST-AS2
Name	UST antisense RNA 2
Location	6q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236591
Ensembl biotype	lncRNA
Entrez	105378047
RNAcentral	URS0000A776CA — lncRNA, 703 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000433442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433442 — 2 exons

Exon	Start	End
ENSE00004051292	149027066	149027780
ENSE00004051293	149032525	149032702

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 85.68.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9291 / max 83.4214, expressed in 245 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76102	0.4848	161
76104	0.1452	58
76105	0.1387	55
76107	0.0964	37
76103	0.0534	21
76106	0.0106	3

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	85.68	gold quality
left adrenal gland	UBERON:0001234	83.09	gold quality
left adrenal gland cortex	UBERON:0035825	82.26	gold quality
adrenal gland	UBERON:0002369	81.66	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	81.20	gold quality
right adrenal gland cortex	UBERON:0035827	80.77	gold quality
right adrenal gland	UBERON:0001233	80.18	gold quality
calcaneal tendon	UBERON:0003701	79.83	gold quality
duodenum	UBERON:0002114	77.50	gold quality
lower esophagus mucosa	UBERON:0035834	76.55	gold quality
monocyte	CL:0000576	76.27	gold quality
sural nerve	UBERON:0015488	75.73	gold quality
adrenal tissue	UBERON:0018303	75.37	gold quality
vermiform appendix	UBERON:0001154	74.94	gold quality
blood	UBERON:0000178	74.29	gold quality
islet of Langerhans	UBERON:0000006	74.06	gold quality
endocervix	UBERON:0000458	73.89	gold quality
small intestine	UBERON:0002108	73.19	gold quality
small intestine Peyer’s patch	UBERON:0003454	72.90	gold quality
lymph node	UBERON:0000029	72.47	gold quality
bone marrow	UBERON:0002371	72.07	gold quality
myometrium	UBERON:0001296	71.05	gold quality
stomach	UBERON:0000945	70.98	gold quality
gastrocnemius	UBERON:0001388	70.87	gold quality
body of pancreas	UBERON:0001150	70.80	gold quality
intestine	UBERON:0000160	70.53	gold quality
Ammon’s horn	UBERON:0001954	70.15	gold quality
kidney	UBERON:0002113	70.08	gold quality
rectum	UBERON:0001052	69.69	gold quality
ectocervix	UBERON:0012249	69.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.