VPS11-DT

Summary

VPS11-DT (VPS11 divergent transcript, HGNC:55227) is a long non-coding RNA gene on chromosome 11q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55227
Approved symbol	VPS11-DT
Name	VPS11 divergent transcript
Location	11q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00019777
Ensembl gene	ENSG00000272186
Ensembl biotype	lncRNA
Entrez	118597841
RNAcentral	URS0002A70E6B — lncRNA, 873 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000607709, ENST00000607857

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607709 — 1 exons

Exon	Start	End
ENSE00003696598	119067374	119067698

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 87.91.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.91	gold quality
colonic epithelium	UBERON:0000397	82.83	gold quality
granulocyte	CL:0000094	77.09	gold quality
corpus callosum	UBERON:0002336	75.13	gold quality
ganglionic eminence	UBERON:0004023	74.99	gold quality
bone marrow	UBERON:0002371	73.56	gold quality
bone marrow cell	CL:0002092	71.92	gold quality
adenohypophysis	UBERON:0002196	71.91	gold quality
pituitary gland	UBERON:0000007	71.56	gold quality
stromal cell of endometrium	CL:0002255	71.41	gold quality
cortical plate	UBERON:0005343	71.30	gold quality
leukocyte	CL:0000738	70.88	gold quality
monocyte	CL:0000576	70.77	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	70.56	gold quality
islet of Langerhans	UBERON:0000006	70.06	gold quality
substantia nigra	UBERON:0002038	69.79	gold quality
apex of heart	UBERON:0002098	69.65	gold quality
muscle of leg	UBERON:0001383	69.56	gold quality
skeletal muscle tissue	UBERON:0001134	69.51	gold quality
gastrocnemius	UBERON:0001388	69.38	gold quality
cerebellum	UBERON:0002037	69.11	gold quality
cerebellar cortex	UBERON:0002129	69.10	gold quality
descending thoracic aorta	UBERON:0002345	69.09	gold quality
cerebellar hemisphere	UBERON:0002245	69.03	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.61	gold quality
ascending aorta	UBERON:0001496	67.86	gold quality
thoracic aorta	UBERON:0001515	67.83	gold quality
popliteal artery	UBERON:0002250	67.57	gold quality
prefrontal cortex	UBERON:0000451	67.54	gold quality
tibial artery	UBERON:0007610	67.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.