VPS33B-DT

Summary

VPS33B-DT (VPS33B divergent transcript, HGNC:51413) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51413
Approved symbol	VPS33B-DT
Name	VPS33B divergent transcript
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000214432
Ensembl biotype	lncRNA
Entrez	101926911
RNAcentral	URS000075E68D — lncRNA, 1637 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000501381, ENST00000556904, ENST00000557804, ENST00000620171, ENST00000716999, ENST00000810070, ENST00000810071, ENST00000810072, ENST00000810073, ENST00000810074, ENST00000810075, ENST00000810076, ENST00000810077

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501381 — 4 exons

Exon	Start	End
ENSE00001967447	91030659	91031140
ENSE00001980685	91022622	91022740
ENSE00002562444	91023313	91023971
ENSE00004031369	91029881	91030241

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 80.03.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2425 / max 12.5258, expressed in 119 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
148542	0.2425	119

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.03	gold quality
cortical plate	UBERON:0005343	68.54	gold quality
ventricular zone	UBERON:0003053	64.06	gold quality
body of pancreas	UBERON:0001150	62.56	gold quality
ganglionic eminence	UBERON:0004023	61.59	gold quality
skeletal muscle tissue	UBERON:0001134	61.20	gold quality
putamen	UBERON:0001874	60.79	gold quality
pancreas	UBERON:0001264	60.23	gold quality
stromal cell of endometrium	CL:0002255	59.78	gold quality
nucleus accumbens	UBERON:0001882	59.77	gold quality
caudate nucleus	UBERON:0001873	59.18	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	58.86	gold quality
prefrontal cortex	UBERON:0000451	58.81	gold quality
cerebellum	UBERON:0002037	58.24	gold quality
cerebellar cortex	UBERON:0002129	58.24	gold quality
cerebellar hemisphere	UBERON:0002245	58.17	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.94	gold quality
anterior cingulate cortex	UBERON:0009835	57.72	gold quality
amygdala	UBERON:0001876	57.69	gold quality
brain	UBERON:0000955	57.67	gold quality
substantia nigra	UBERON:0002038	57.46	gold quality
cerebral cortex	UBERON:0000956	57.36	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	57.23	gold quality
frontal cortex	UBERON:0001870	57.19	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.17	gold quality
bone marrow	UBERON:0002371	57.04	gold quality
Ammon’s horn	UBERON:0001954	57.02	gold quality
lymph node	UBERON:0000029	55.92	gold quality
muscle tissue	UBERON:0002385	55.80	gold quality
hypothalamus	UBERON:0001898	55.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.39

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.