VPS53-AS1

Summary

VPS53-AS1 (VPS53 antisense RNA 1, HGNC:58554) is a long non-coding RNA gene on chromosome 17p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58554
Approved symbol	VPS53-AS1
Name	VPS53 antisense RNA 1
Location	17p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263300
Ensembl biotype	lncRNA
Entrez	124903890

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000570974

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000570974 — 2 exons

Exon	Start	End
ENSE00002655313	540389	540576
ENSE00002670541	523140	523429

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 79.27.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.27	silver quality
sural nerve	UBERON:0015488	70.91	gold quality
bone marrow cell	CL:0002092	69.23	silver quality
bone marrow	UBERON:0002371	66.15	gold quality
muscle tissue	UBERON:0002385	65.77	gold quality
skeletal muscle tissue	UBERON:0001134	64.69	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.14	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.01	gold quality
calcaneal tendon	UBERON:0003701	58.65	gold quality
corpus callosum	UBERON:0002336	58.53	gold quality
blood	UBERON:0000178	58.50	gold quality
monocyte	CL:0000576	58.17	gold quality
primary visual cortex	UBERON:0002436	56.57	gold quality
lymph node	UBERON:0000029	55.97	gold quality
vermiform appendix	UBERON:0001154	55.97	gold quality
islet of Langerhans	UBERON:0000006	54.96	gold quality
liver	UBERON:0002107	54.61	gold quality
skin of abdomen	UBERON:0001416	54.44	gold quality
zone of skin	UBERON:0000014	54.35	gold quality
muscle of leg	UBERON:0001383	54.24	gold quality
lower esophagus mucosa	UBERON:0035834	54.10	gold quality
skin of leg	UBERON:0001511	53.97	gold quality
prefrontal cortex	UBERON:0000451	53.92	gold quality
tonsil	UBERON:0002372	53.13	gold quality
descending thoracic aorta	UBERON:0002345	52.80	gold quality
gastrocnemius	UBERON:0001388	52.78	gold quality
placenta	UBERON:0001987	52.25	gold quality
testis	UBERON:0000473	52.24	gold quality
left testis	UBERON:0004533	52.14	gold quality
right lobe of liver	UBERON:0001114	51.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.