VSTM2A-OT1

Summary

VSTM2A-OT1 (VSTM2A overlapping transcript 1, HGNC:50770) is a long non-coding RNA gene on chromosome 7p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50770
Approved symbol	VSTM2A-OT1
Name	VSTM2A overlapping transcript 1
Location	7p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224223
Ensembl biotype	lncRNA
Entrez	285878
RNAcentral	URS000075E53F — lncRNA, 3061 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000456049

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456049 — 4 exons

Exon	Start	End
ENSE00001626971	54571266	54571726
ENSE00001648174	54557850	54559971
ENSE00001755008	54556970	54557295
ENSE00001773570	54570770	54570891

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 77.78.

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.78	gold quality
primary visual cortex	UBERON:0002436	71.73	gold quality
superior frontal gyrus	UBERON:0002661	69.90	gold quality
prefrontal cortex	UBERON:0000451	68.30	gold quality
frontal cortex	UBERON:0001870	65.82	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.38	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.89	gold quality
cerebral cortex	UBERON:0000956	63.26	gold quality
cortical plate	UBERON:0005343	62.35	gold quality
right frontal lobe	UBERON:0002810	61.77	gold quality
corpus callosum	UBERON:0002336	61.40	gold quality
ganglionic eminence	UBERON:0004023	61.07	gold quality
anterior cingulate cortex	UBERON:0009835	61.03	gold quality
cerebellar hemisphere	UBERON:0002245	61.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.82	gold quality
ventricular zone	UBERON:0003053	60.63	gold quality
nucleus accumbens	UBERON:0001882	60.06	gold quality
brain	UBERON:0000955	59.75	gold quality
temporal lobe	UBERON:0001871	56.79	gold quality
amygdala	UBERON:0001876	56.66	gold quality
hypothalamus	UBERON:0001898	55.36	gold quality
caudate nucleus	UBERON:0001873	54.89	gold quality
multicellular organism	UBERON:0000468	54.47	gold quality
putamen	UBERON:0001874	53.86	gold quality
Ammon’s horn	UBERON:0001954	53.44	gold quality
urinary bladder	UBERON:0001255	52.37	silver quality
adrenal tissue	UBERON:0018303	50.35	silver quality
islet of Langerhans	UBERON:0000006	48.83	gold quality
rectum	UBERON:0001052	48.61	gold quality
duodenum	UBERON:0002114	48.13	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.