VSTM2B-DT

Summary

VSTM2B-DT (VSTM2B divergent transcript, HGNC:27615) is a long non-coding RNA gene on chromosome 19q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27615
Approved symbol	VSTM2B-DT
Name	VSTM2B divergent transcript
Location	19q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264515
Ensembl biotype	lncRNA
Entrez	284395
RNAcentral	URS00025E34A3 — lncRNA, 2582 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 30 lncRNA, 2 retained_intron

ENST00000577849, ENST00000579268, ENST00000582581, ENST00000623523, ENST00000660387, ENST00000664318, ENST00000690107, ENST00000716172, ENST00000716173, ENST00000804084, ENST00000804085, ENST00000804086, ENST00000804087, ENST00000804088, ENST00000804089, ENST00000804090, ENST00000804091, ENST00000804092, ENST00000804093, ENST00000804094, ENST00000804095, ENST00000804096, ENST00000804097, ENST00000804098, ENST00000804099, ENST00000804100, ENST00000804101, ENST00000804102, ENST00000804103, ENST00000804104, ENST00000804105, ENST00000804106

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577849 — 3 exons

Exon	Start	End
ENSE00002716638	29428731	29428810
ENSE00004195157	29412231	29412966
ENSE00004195174	29525424	29525858

Expression profiles

Bgee: expression breadth broad, 81 present calls, max score 78.79.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0925 / max 19.3095, expressed in 50 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
180354	0.0925	50

Top tissues by expression

189 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.79	gold quality
right frontal lobe	UBERON:0002810	70.79	gold quality
anterior cingulate cortex	UBERON:0009835	70.48	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.42	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	68.87	gold quality
nucleus accumbens	UBERON:0001882	68.85	gold quality
amygdala	UBERON:0001876	67.38	gold quality
spinal cord	UBERON:0002240	66.28	gold quality
cortical plate	UBERON:0005343	65.95	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.61	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	65.50	gold quality
putamen	UBERON:0001874	65.18	gold quality
caudate nucleus	UBERON:0001873	64.63	gold quality
cerebellar hemisphere	UBERON:0002245	64.33	gold quality
neocortex	UBERON:0001950	64.14	gold quality
cerebellar cortex	UBERON:0002129	64.06	gold quality
prefrontal cortex	UBERON:0000451	63.10	gold quality
frontal cortex	UBERON:0001870	62.97	gold quality
cerebral cortex	UBERON:0000956	62.54	gold quality
cerebellum	UBERON:0002037	62.45	gold quality
forebrain	UBERON:0001890	62.41	gold quality
brain	UBERON:0000955	61.92	gold quality
hypothalamus	UBERON:0001898	61.90	gold quality
substantia nigra	UBERON:0002038	61.67	gold quality
Ammon’s horn	UBERON:0001954	61.48	gold quality
metanephros	UBERON:0000081	60.70	gold quality
temporal lobe	UBERON:0001871	59.70	gold quality
granulocyte	CL:0000094	59.54	gold quality
midbrain	UBERON:0001891	59.33	gold quality
endothelial cell	CL:0000115	58.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.