VTRNA1-3

Summary

VTRNA1-3 (vault RNA 1-3, HGNC:12656) is a gene on chromosome 5q31.3.

At a glance

• Gene type: non-coding (vault_RNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:12656
Approved symbol	VTRNA1-3
Name	vault RNA 1-3
Location	5q31.3
Locus type	RNA, vault
Status	Approved
Aliases	hvg-3, HVG3, VR3
Ensembl gene	ENSG00000202515
Ensembl biotype	vault_RNA
OMIM	612697
Entrez	56662
RNAcentral	URS000058CD99 — ncRNA, 88 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 vault_RNA

ENST00000365645

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000365645 — 1 exons

Exon	Start	End
ENSE00001808502	140726158	140726246

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 96.97.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6086 / max 163.1378, expressed in 229 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
58937	0.6086	229

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	96.97	gold quality
sural nerve	UBERON:0015488	90.42	gold quality
granulocyte	CL:0000094	89.21	gold quality
calcaneal tendon	UBERON:0003701	85.35	gold quality
liver	UBERON:0002107	83.07	gold quality
islet of Langerhans	UBERON:0000006	82.46	gold quality
bone marrow	UBERON:0002371	78.90	gold quality
vermiform appendix	UBERON:0001154	78.75	gold quality
blood	UBERON:0000178	78.65	gold quality
placenta	UBERON:0001987	78.23	gold quality
kidney	UBERON:0002113	78.04	gold quality
omental fat pad	UBERON:0010414	77.97	gold quality
stomach	UBERON:0000945	77.30	gold quality
adult mammalian kidney	UBERON:0000082	76.83	gold quality
adrenal gland	UBERON:0002369	75.93	gold quality
body of pancreas	UBERON:0001150	75.76	gold quality
muscle of leg	UBERON:0001383	75.56	gold quality
endometrium	UBERON:0001295	75.28	gold quality
heart	UBERON:0000948	74.67	gold quality
body of stomach	UBERON:0001161	74.65	gold quality
adipose tissue	UBERON:0001013	74.42	gold quality
monocyte	CL:0000576	74.19	gold quality
gastrocnemius	UBERON:0001388	74.02	gold quality
heart left ventricle	UBERON:0002084	73.97	gold quality
right adrenal gland	UBERON:0001233	73.57	gold quality
left adrenal gland	UBERON:0001234	73.21	gold quality
left ovary	UBERON:0002119	72.95	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.52	gold quality
smooth muscle tissue	UBERON:0001135	71.69	gold quality
left adrenal gland cortex	UBERON:0035825	71.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	11.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (7): VTRNA3-1P (ENSG00000199422), VTRNA1-1 (ENSG00000199990), VTRNA1-2 (ENSG00000202111), VTRNA2-2P (ENSG00000251900), Vault (ENSG00000252283), Vault (ENSG00000252328), Vault (ENSG00000252485)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.