VWC2L-IT1

Summary

VWC2L-IT1 (VWC2L intronic transcript 1, HGNC:41508) is a long non-coding RNA gene on chromosome 2q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41508
Approved symbol	VWC2L-IT1
Name	VWC2L intronic transcript 1
Location	2q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224257
Ensembl biotype	lncRNA
Entrez	100885780
RNAcentral	URS000075B4FE — lncRNA, 481 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000416430

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416430 — 4 exons

Exon	Start	End
ENSE00001741295	214510196	214510215
ENSE00001770425	214536762	214536890
ENSE00001785754	214533996	214534145
ENSE00001789448	214525174	214525341

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 59.88.

Top tissues by expression

52 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
islet of Langerhans	UBERON:0000006	59.88	gold quality
prefrontal cortex	UBERON:0000451	59.54	gold quality
blood	UBERON:0000178	54.69	silver quality
gastrocnemius	UBERON:0001388	53.89	gold quality
monocyte	CL:0000576	52.51	silver quality
frontal cortex	UBERON:0001870	51.99	gold quality
calcaneal tendon	UBERON:0003701	51.82	silver quality
thyroid gland	UBERON:0002046	51.49	gold quality
superior frontal gyrus	UBERON:0002661	50.55	gold quality
cerebral cortex	UBERON:0000956	48.20	gold quality
heart left ventricle	UBERON:0002084	46.48	gold quality
body of stomach	UBERON:0001161	45.81	gold quality
left ovary	UBERON:0002119	45.71	gold quality
brain	UBERON:0000955	45.16	gold quality
esophagus mucosa	UBERON:0002469	45.01	silver quality
corpus callosum	UBERON:0002336	44.94	silver quality
prostate gland	UBERON:0002367	44.65	gold quality
vagina	UBERON:0000996	44.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	44.36	gold quality
right atrium auricular region	UBERON:0006631	44.10	silver quality
Brodmann (1909) area 9	UBERON:0013540	44.01	silver quality
stomach	UBERON:0000945	43.96	gold quality
right coronary artery	UBERON:0001625	43.61	gold quality
skin of abdomen	UBERON:0001416	43.51	silver quality
transverse colon	UBERON:0001157	42.89	gold quality
tibial artery	UBERON:0007610	42.88	silver quality
small intestine Peyer’s patch	UBERON:0003454	42.81	silver quality
body of pancreas	UBERON:0001150	42.76	silver quality
intestine	UBERON:0000160	42.64	silver quality
substantia nigra	UBERON:0002038	41.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.