WARS2-AS1

Summary

WARS2-AS1 (WARS2 antisense RNA 1, HGNC:40612) is a long non-coding RNA gene on chromosome 1p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40612
Approved symbol	WARS2-AS1
Name	WARS2 antisense RNA 1
Location	1p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231365
Ensembl biotype	lncRNA
Entrez	101929147
RNAcentral	URS00007E486B — lncRNA, 2519 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000413531, ENST00000418015, ENST00000425884, ENST00000440150, ENST00000445565, ENST00000457043, ENST00000667138, ENST00000667936, ENST00000670000, ENST00000685192, ENST00000688395, ENST00000715919

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413531 — 5 exons

Exon	Start	End
ENSE00001608131	119150565	119150746
ENSE00001776259	119141747	119141813
ENSE00001784202	119146953	119147069
ENSE00001784465	119233458	119234181
ENSE00004028337	119140730	119140793

Expression profiles

Bgee: expression breadth ubiquitous, 173 present calls, max score 88.92.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 10.6389 / max 224.4737, expressed in 1759 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4907	9.5101	1744
4910	0.6627	282
4909	0.3867	197
4908	0.0793	18

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	88.92	gold quality
calcaneal tendon	UBERON:0003701	87.98	gold quality
right uterine tube	UBERON:0001302	87.55	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.15	gold quality
left ovary	UBERON:0002119	84.87	gold quality
cerebellar hemisphere	UBERON:0002245	84.84	gold quality
right lobe of thyroid gland	UBERON:0001119	84.78	gold quality
cerebellar cortex	UBERON:0002129	84.57	gold quality
metanephros cortex	UBERON:0010533	84.02	gold quality
left lobe of thyroid gland	UBERON:0001120	83.99	gold quality
right adrenal gland cortex	UBERON:0035827	83.52	gold quality
body of uterus	UBERON:0009853	83.18	gold quality
right adrenal gland	UBERON:0001233	83.10	gold quality
right ovary	UBERON:0002118	83.04	gold quality
tibial nerve	UBERON:0001323	82.92	gold quality
thyroid gland	UBERON:0002046	82.80	gold quality
mucosa of transverse colon	UBERON:0004991	82.70	gold quality
left adrenal gland	UBERON:0001234	82.44	gold quality
adrenal tissue	UBERON:0018303	82.33	gold quality
left adrenal gland cortex	UBERON:0035825	82.21	gold quality
colonic epithelium	UBERON:0000397	81.86	gold quality
cerebellum	UBERON:0002037	81.40	gold quality
right lobe of liver	UBERON:0001114	81.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.24	gold quality
small intestine Peyer’s patch	UBERON:0003454	81.12	gold quality
adenohypophysis	UBERON:0002196	80.93	gold quality
transverse colon	UBERON:0001157	80.82	gold quality
endocervix	UBERON:0000458	80.69	gold quality
lower esophagus mucosa	UBERON:0035834	80.69	gold quality
ectocervix	UBERON:0012249	80.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.