WDR35-DT

Summary

WDR35-DT (WDR35 divergent transcript, HGNC:55818) is a long non-coding RNA gene on chromosome 2p24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55818
Approved symbol	WDR35-DT
Name	WDR35 divergent transcript
Location	2p24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227210
Ensembl biotype	lncRNA
Entrez	101928222
RNAcentral	URS000075CEAA — lncRNA, 1150 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000416575, ENST00000658200, ENST00000737626, ENST00000737627, ENST00000737628, ENST00000737629, ENST00000737630, ENST00000737631

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416575 — 3 exons

Exon	Start	End
ENSE00001669659	19999206	19999277
ENSE00004072103	20004020	20004821
ENSE00004072106	19990165	19990494

Expression profiles

Bgee: expression breadth ubiquitous, 141 present calls, max score 80.24.

Top tissues by expression

233 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.24	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.70	gold quality
sperm	CL:0000019	71.91	gold quality
ventricular zone	UBERON:0003053	65.96	gold quality
right uterine tube	UBERON:0001302	65.46	gold quality
vena cava	UBERON:0004087	63.64	silver quality
epithelium of nasopharynx	UBERON:0001951	61.57	gold quality
islet of Langerhans	UBERON:0000006	61.30	gold quality
oviduct epithelium	UBERON:0004804	61.10	gold quality
endothelial cell	CL:0000115	60.97	gold quality
adenohypophysis	UBERON:0002196	60.77	gold quality
pituitary gland	UBERON:0000007	60.61	gold quality
cortical plate	UBERON:0005343	60.56	gold quality
nasal cavity epithelium	UBERON:0005384	60.56	gold quality
ganglionic eminence	UBERON:0004023	60.38	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	60.17	gold quality
sural nerve	UBERON:0015488	60.14	silver quality
buccal mucosa cell	CL:0002336	59.83	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	59.43	gold quality
right testis	UBERON:0004534	59.38	gold quality
skeletal muscle tissue	UBERON:0001134	59.32	gold quality
stromal cell of endometrium	CL:0002255	59.29	gold quality
metanephros	UBERON:0000081	58.69	gold quality
biceps brachii	UBERON:0001507	58.67	gold quality
metanephros cortex	UBERON:0010533	58.60	gold quality
caecum	UBERON:0001153	58.51	gold quality
substantia nigra pars compacta	UBERON:0001965	58.49	gold quality
myocardium	UBERON:0002349	58.44	gold quality
left testis	UBERON:0004533	58.26	gold quality
testis	UBERON:0000473	58.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.