WDR5-DT

Summary

WDR5-DT (WDR5 divergent transcript, HGNC:55141) is a long non-coding RNA gene on chromosome 9q34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55141
Approved symbol	WDR5-DT
Name	WDR5 divergent transcript
Location	9q34.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273249
Ensembl biotype	lncRNA
Entrez	118568806
RNAcentral	URS00026A1E17 — lncRNA, 1821 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000607930, ENST00000610187, ENST00000729260, ENST00000729261, ENST00000729262, ENST00000729263, ENST00000729264, ENST00000729265

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607930 — 2 exons

Exon	Start	End
ENSE00004056633	134134065	134134370
ENSE00004056644	134135186	134135649

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 84.40.

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.40	gold quality
bone marrow cell	CL:0002092	70.04	silver quality
right uterine tube	UBERON:0001302	63.83	gold quality
ventricular zone	UBERON:0003053	63.69	gold quality
pituitary gland	UBERON:0000007	63.57	gold quality
left ovary	UBERON:0002119	61.94	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.71	gold quality
ovary	UBERON:0000992	61.44	gold quality
cerebellar hemisphere	UBERON:0002245	61.42	gold quality
adenohypophysis	UBERON:0002196	61.39	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.30	gold quality
cerebellar cortex	UBERON:0002129	61.19	gold quality
ganglionic eminence	UBERON:0004023	61.18	gold quality
cerebellum	UBERON:0002037	61.09	gold quality
right lung	UBERON:0002167	60.52	gold quality
fundus of stomach	UBERON:0001160	60.45	gold quality
right ovary	UBERON:0002118	60.38	gold quality
right coronary artery	UBERON:0001625	59.86	gold quality
right lobe of thyroid gland	UBERON:0001119	59.84	gold quality
thyroid gland	UBERON:0002046	59.73	gold quality
mucosa of transverse colon	UBERON:0004991	59.64	gold quality
left lobe of thyroid gland	UBERON:0001120	59.14	gold quality
metanephros cortex	UBERON:0010533	59.05	gold quality
cortical plate	UBERON:0005343	59.02	gold quality
body of pancreas	UBERON:0001150	59.01	gold quality
pancreas	UBERON:0001264	58.94	gold quality
granulocyte	CL:0000094	58.74	gold quality
duodenum	UBERON:0002114	58.68	gold quality
apex of heart	UBERON:0002098	58.47	gold quality
prefrontal cortex	UBERON:0000451	58.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.