WDR5B-DT

Summary

WDR5B-DT (WDR5B divergent transcript, HGNC:55192) is a long non-coding RNA gene on chromosome 3q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55192
Approved symbol	WDR5B-DT
Name	WDR5B divergent transcript
Location	3q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272758
Ensembl biotype	lncRNA
Entrez	102723582
RNAcentral	URS00007E3FA0 — lncRNA, 621 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000608015, ENST00000608346, ENST00000608465, ENST00000608756, ENST00000609469, ENST00000667395, ENST00000686885, ENST00000831938, ENST00000831939, ENST00000831940, ENST00000831941, ENST00000831942, ENST00000831943, ENST00000831944, ENST00000831945, ENST00000831946

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608015 — 3 exons

Exon	Start	End
ENSE00003703393	122425848	122426344
ENSE00003705155	122416225	122416250
ENSE00003705778	122425607	122425658

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 92.96.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.1882 / max 117.1167, expressed in 1474 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
38234	4.1882	1474

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	92.96	gold quality
skeletal muscle tissue	UBERON:0001134	91.17	gold quality
ventricular zone	UBERON:0003053	90.92	gold quality
gastrocnemius	UBERON:0001388	90.74	gold quality
muscle of leg	UBERON:0001383	90.62	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.83	gold quality
ganglionic eminence	UBERON:0004023	89.50	gold quality
islet of Langerhans	UBERON:0000006	89.22	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.14	gold quality
pituitary gland	UBERON:0000007	88.81	gold quality
muscle tissue	UBERON:0002385	88.81	gold quality
right lobe of liver	UBERON:0001114	88.55	gold quality
blood	UBERON:0000178	88.32	gold quality
lower esophagus mucosa	UBERON:0035834	88.30	gold quality
adenohypophysis	UBERON:0002196	88.22	gold quality
monocyte	CL:0000576	88.17	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	88.01	gold quality
leukocyte	CL:0000738	87.90	gold quality
pancreas	UBERON:0001264	87.90	gold quality
body of pancreas	UBERON:0001150	87.67	gold quality
stromal cell of endometrium	CL:0002255	87.65	gold quality
prefrontal cortex	UBERON:0000451	87.48	gold quality
left ovary	UBERON:0002119	87.46	gold quality
cortical plate	UBERON:0005343	87.40	gold quality
left adrenal gland cortex	UBERON:0035825	87.05	gold quality
ovary	UBERON:0000992	87.02	gold quality
right adrenal gland cortex	UBERON:0035827	86.92	gold quality
right adrenal gland	UBERON:0001233	86.88	gold quality
liver	UBERON:0002107	86.87	gold quality
calcaneal tendon	UBERON:0003701	86.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.