WDR7-OT1

Summary

WDR7-OT1 (WDR7 overlapping transcript 1, HGNC:45131) is a long non-coding RNA gene on chromosome 18q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45131
Approved symbol	WDR7-OT1
Name	WDR7 overlapping transcript 1
Location	18q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267225
Ensembl biotype	lncRNA
Entrez	107985140
RNAcentral	URS00000449B6 — lncRNA, 565 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000592032

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000592032 — 3 exons

Exon	Start	End
ENSE00001145077	57027832	57028220
ENSE00002751331	57038808	57038845
ENSE00002854517	57029825	57029962

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 86.80.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.80	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.75	gold quality
cortical plate	UBERON:0005343	75.21	gold quality
left testis	UBERON:0004533	71.01	gold quality
ganglionic eminence	UBERON:0004023	70.81	gold quality
testis	UBERON:0000473	70.20	gold quality
right testis	UBERON:0004534	69.99	gold quality
skeletal muscle tissue	UBERON:0001134	68.18	gold quality
prefrontal cortex	UBERON:0000451	66.25	gold quality
placenta	UBERON:0001987	66.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.15	gold quality
duodenum	UBERON:0002114	65.48	gold quality
islet of Langerhans	UBERON:0000006	64.81	gold quality
gall bladder	UBERON:0002110	64.19	gold quality
right coronary artery	UBERON:0001625	63.81	gold quality
ventricular zone	UBERON:0003053	63.04	gold quality
primary visual cortex	UBERON:0002436	61.61	gold quality
lymph node	UBERON:0000029	61.43	gold quality
granulocyte	CL:0000094	61.19	gold quality
vermiform appendix	UBERON:0001154	60.34	gold quality
bone marrow	UBERON:0002371	60.33	gold quality
muscle of leg	UBERON:0001383	60.19	gold quality
gastrocnemius	UBERON:0001388	59.95	gold quality
pancreas	UBERON:0001264	59.93	gold quality
monocyte	CL:0000576	59.56	gold quality
descending thoracic aorta	UBERON:0002345	58.86	gold quality
tibial artery	UBERON:0007610	58.61	gold quality
popliteal artery	UBERON:0002250	58.57	gold quality
rectum	UBERON:0001052	58.02	gold quality
right lobe of thyroid gland	UBERON:0001119	57.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.54

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.