WFS1-AS1

Summary

WFS1-AS1 (WFS1 antisense RNA 1, HGNC:58722) is a long non-coding RNA gene on chromosome 4p16.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58722
Approved symbol	WFS1-AS1
Name	WFS1 antisense RNA 1
Location	4p16.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286176
Ensembl biotype	lncRNA
Entrez	143365924

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000650929, ENST00000661896, ENST00000665800

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000650929 — 3 exons

Exon	Start	End
ENSE00003843020	6303915	6304077
ENSE00003844561	6307267	6308636
ENSE00003845050	6302886	6303338

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 78.75.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.75	gold quality
cerebellum	UBERON:0002037	71.11	gold quality
cerebellar hemisphere	UBERON:0002245	71.01	gold quality
cerebellar cortex	UBERON:0002129	71.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.62	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.38	silver quality
sural nerve	UBERON:0015488	68.01	gold quality
endometrium	UBERON:0001295	65.77	gold quality
nucleus accumbens	UBERON:0001882	65.22	gold quality
stromal cell of endometrium	CL:0002255	64.62	gold quality
islet of Langerhans	UBERON:0000006	61.72	gold quality
ventricular zone	UBERON:0003053	60.72	gold quality
prefrontal cortex	UBERON:0000451	59.87	gold quality
superior frontal gyrus	UBERON:0002661	59.34	gold quality
body of uterus	UBERON:0009853	59.20	gold quality
myometrium	UBERON:0001296	59.13	gold quality
brain	UBERON:0000955	58.67	gold quality
frontal cortex	UBERON:0001870	58.65	gold quality
right ovary	UBERON:0002118	58.42	gold quality
ovary	UBERON:0000992	58.33	gold quality
mucosa of stomach	UBERON:0001199	58.20	gold quality
putamen	UBERON:0001874	58.13	gold quality
left ovary	UBERON:0002119	58.08	gold quality
placenta	UBERON:0001987	58.07	gold quality
popliteal artery	UBERON:0002250	58.06	gold quality
tibial artery	UBERON:0007610	58.06	gold quality
left uterine tube	UBERON:0001303	57.82	gold quality
skeletal muscle tissue	UBERON:0001134	57.66	gold quality
fallopian tube	UBERON:0003889	57.54	gold quality
caudate nucleus	UBERON:0001873	57.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.