WWC2-AS1

Summary

WWC2-AS1 (WWC2 antisense RNA 1, HGNC:41041) is a long non-coding RNA gene on chromosome 4q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41041
Approved symbol	WWC2-AS1
Name	WWC2 antisense RNA 1
Location	4q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251128
Ensembl biotype	lncRNA
OMIM	620088
Entrez	101928734
RNAcentral	URS00007E4B6C — lncRNA, 419 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000511846

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511846 — 2 exons

Exon	Start	End
ENSE00002020346	183240524	183240634
ENSE00002078247	183233628	183233920

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 95.51.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0203 / max 12.2261, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55087	0.0203	3

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.51	gold quality
sural nerve	UBERON:0015488	72.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.09	gold quality
monocyte	CL:0000576	63.29	gold quality
liver	UBERON:0002107	61.54	gold quality
calcaneal tendon	UBERON:0003701	61.19	gold quality
islet of Langerhans	UBERON:0000006	57.93	gold quality
tonsil	UBERON:0002372	57.86	silver quality
vermiform appendix	UBERON:0001154	57.80	gold quality
adrenal tissue	UBERON:0018303	56.62	gold quality
superior frontal gyrus	UBERON:0002661	55.93	gold quality
kidney	UBERON:0002113	55.17	gold quality
blood	UBERON:0000178	54.61	gold quality
endometrium	UBERON:0001295	54.55	silver quality
cortex of kidney	UBERON:0001225	53.58	gold quality
pancreas	UBERON:0001264	53.46	gold quality
corpus callosum	UBERON:0002336	52.60	gold quality
gastrocnemius	UBERON:0001388	52.50	gold quality
body of pancreas	UBERON:0001150	52.10	gold quality
urinary bladder	UBERON:0001255	51.64	silver quality
heart	UBERON:0000948	51.29	gold quality
prefrontal cortex	UBERON:0000451	51.28	gold quality
heart left ventricle	UBERON:0002084	51.09	gold quality
right lobe of liver	UBERON:0001114	50.60	gold quality
adrenal gland	UBERON:0002369	50.38	gold quality
pituitary gland	UBERON:0000007	50.21	gold quality
endocervix	UBERON:0000458	49.87	gold quality
adult mammalian kidney	UBERON:0000082	49.73	gold quality
lung	UBERON:0002048	49.65	gold quality
stomach	UBERON:0000945	49.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.