WWOX-AS2

Summary

WWOX-AS2 (WWOX antisense RNA 2, HGNC:58302) is a long non-coding RNA gene on chromosome 16q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58302
Approved symbol	WWOX-AS2
Name	WWOX antisense RNA 2
Location	16q23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260733
Ensembl biotype	lncRNA
Entrez	124903730
RNAcentral	URS00001A231E — lncRNA, 719 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000563408

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563408 — 3 exons

Exon	Start	End
ENSE00002594529	78503663	78503798
ENSE00002615741	78506492	78506568
ENSE00002616545	78495926	78496431

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 86.89.

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.89	gold quality
bone marrow cell	CL:0002092	73.78	gold quality
tonsil	UBERON:0002372	66.31	gold quality
calcaneal tendon	UBERON:0003701	65.35	gold quality
corpus callosum	UBERON:0002336	65.21	gold quality
skeletal muscle tissue	UBERON:0001134	63.20	silver quality
colonic epithelium	UBERON:0000397	62.96	silver quality
urinary bladder	UBERON:0001255	60.76	silver quality
liver	UBERON:0002107	60.64	gold quality
uterine cervix	UBERON:0000002	59.59	gold quality
kidney	UBERON:0002113	58.04	gold quality
adrenal tissue	UBERON:0018303	58.03	gold quality
adrenal gland	UBERON:0002369	55.54	gold quality
adult mammalian kidney	UBERON:0000082	55.37	gold quality
blood	UBERON:0000178	54.86	silver quality
stomach	UBERON:0000945	54.79	gold quality
cortex of kidney	UBERON:0001225	53.73	gold quality
right lobe of liver	UBERON:0001114	53.35	gold quality
monocyte	CL:0000576	52.95	silver quality
muscle of leg	UBERON:0001383	52.73	gold quality
islet of Langerhans	UBERON:0000006	52.65	gold quality
lung	UBERON:0002048	52.48	gold quality
thoracic mammary gland	UBERON:0005200	51.94	silver quality
prefrontal cortex	UBERON:0000451	50.63	gold quality
superior frontal gyrus	UBERON:0002661	49.06	gold quality
heart	UBERON:0000948	48.72	gold quality
intestine	UBERON:0000160	48.52	gold quality
multicellular organism	UBERON:0000468	47.53	gold quality
ectocervix	UBERON:0012249	47.26	gold quality
endometrium	UBERON:0001295	46.63	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.