WWP1-AS1

Summary

WWP1-AS1 (WWP1 antisense RNA 1, HGNC:55520) is a long non-coding RNA gene on chromosome 8q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55520
Approved symbol	WWP1-AS1
Name	WWP1 antisense RNA 1
Location	8q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC103760.1
Ensembl gene	ENSG00000254231
Ensembl biotype	lncRNA
Entrez	105375624
RNAcentral	URS0000EEC5D7 — lncRNA, 5389 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 3 lncRNA, 1 retained_intron

ENST00000521326, ENST00000523218, ENST00000668794, ENST00000775416

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000521326 — 4 exons

Exon	Start	End
ENSE00002105751	86335703	86335761
ENSE00002133251	86333274	86334199
ENSE00002135639	86338120	86338387
ENSE00003880691	86343082	86343429

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 77.34.

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	77.34	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.71	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.70	gold quality
gall bladder	UBERON:0002110	71.26	gold quality
liver	UBERON:0002107	69.64	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.75	gold quality
rectum	UBERON:0001052	62.03	gold quality
adult mammalian kidney	UBERON:0000082	62.01	gold quality
colonic epithelium	UBERON:0000397	61.79	silver quality
sural nerve	UBERON:0015488	61.65	silver quality
metanephros cortex	UBERON:0010533	61.21	gold quality
mucosa of transverse colon	UBERON:0004991	60.06	gold quality
upper leg skin	UBERON:0004262	59.76	gold quality
ganglionic eminence	UBERON:0004023	59.35	gold quality
ventricular zone	UBERON:0003053	58.98	silver quality
cortex of kidney	UBERON:0001225	58.66	gold quality
kidney	UBERON:0002113	57.77	gold quality
muscle of leg	UBERON:0001383	57.69	gold quality
body of pancreas	UBERON:0001150	57.27	gold quality
right adrenal gland cortex	UBERON:0035827	57.18	gold quality
pancreas	UBERON:0001264	56.75	gold quality
gastrocnemius	UBERON:0001388	56.51	gold quality
transverse colon	UBERON:0001157	56.34	gold quality
apex of heart	UBERON:0002098	56.09	gold quality
lymph node	UBERON:0000029	55.99	gold quality
leukocyte	CL:0000738	55.89	gold quality
adrenal tissue	UBERON:0018303	55.80	gold quality
putamen	UBERON:0001874	55.60	gold quality
monocyte	CL:0000576	55.41	gold quality
corpus epididymis	UBERON:0004359	55.39	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.